Gene Symbol | HINFP |
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Entrez Gene | 25988 |
Alt Symbol | HiNF-P, MIZF, ZNF743 |
Species | Human |
Gene Type | protein-coding |
Description | histone H4 transcription factor |
Other Description | MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein|MBD2-interacting zinc finger 1|MBD2-interacting zinc finger protein|histone H4 gene-specific protein HiNF-P|histone nuclear factor P|methyl-CpG-binding protein 2-interacting zinc finger protein |
Swissprots | E9PQF4 Q9BQA5 B4DWB4 Q96E65 Q9Y4M7 B3KPH6 |
Accessions | EAW67460 EAW67461 EAW67462 EAW67463 Q9BQA5 AK056362 BAG51688 AK092869 AK300288 BAG62045 AK301452 BAG62976 AL080201 CAB45773 BC001073 AAH01073 BC001945 AAH01945 BC012856 AAH12856 BC017234 AAH17234 BF726036 BG821695 DC326345 DQ894647 ABM85573 XM_006718814 XP_006718877 XM_011542744 XP_011541046 XM_011542745 XP_011541047 XM_011542746 XP_011541048 NM_001243259 NP_001230188 NM_015517 NP_056332 NM_198971 NP_945322 |
Function | Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:14752047, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:17163457, ECO:0000269|PubMed:17974976, ECO:0000269|PubMed:18850719}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:18850719}. Note=Associated with discrete nuclear foci. |
Tissue Specificity | Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver. {ECO:0000269|PubMed:11553631}. |
HiNF-P (A-19) - sc-49818 from Santa Cruz Biotechnology
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HiNF-P (C-5) - sc-373855 from Santa Cruz Biotechnology
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HiNF-P (H-207) - sc-292278 from Santa Cruz Biotechnology
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HiNF-P (W-19) - sc-49821 from Santa Cruz Biotechnology
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Anti-HINFP Antibody (aa317-346, AP) - LS-C215066 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346, APC) - LS-C215067 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346, Biotin) - LS-C215068 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346, Azide-free, HRP) - LS-C215070 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346, PE) - LS-C215071 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346, FITC) - LS-C215069 from LifeSpan Bioscience
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Anti-HINFP Antibody - LS-C308235 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa316-346) - LS-C321952 from LifeSpan Bioscience
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Anti-HINFP Antibody - LS-C341992 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa180-229) - LS-C101398 from LifeSpan Bioscience
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Anti-HINFP Antibody (C-Terminus) - LS-C101735 from LifeSpan Bioscience
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Anti-HINFP Antibody (aa317-346) - LS-C166871 from LifeSpan Bioscience
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Anti-HINFP Antibody - LS-C740 from LifeSpan Bioscience
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HINFP Antibody - NB100-56628 from Novus Biologicals
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HINFP Antibody - NBP2-32582 from Novus Biologicals
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HINFP Antibody - H00025988-B01P from Novus Biologicals
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HINFP Antibody - H00025988-B01 from Novus Biologicals
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Anti-HINFP antibody produced in rabbit - HPA061008 from Sigma-Aldrich
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Anti-MIZF (ab2) antibody produced in rabbit - SAB2101482 from Sigma-Aldrich
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Anti-MIZF antibody produced in mouse - SAB1407271 from Sigma-Aldrich
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ANTI-HINFP (CENTER) antibody produced in rabbit - SAB1306620 from Sigma-Aldrich
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