HINFP
| Gene Symbol | HINFP |
|---|---|
| Entrez Gene | 25988 |
| Alt Symbol | HiNF-P, MIZF, ZNF743 |
| Species | Human |
| Gene Type | protein-coding |
| Description | histone H4 transcription factor |
| Other Description | MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein|MBD2-interacting zinc finger 1|MBD2-interacting zinc finger protein|histone H4 gene-specific protein HiNF-P|histone nuclear factor P|methyl-CpG-binding protein 2-interacting zinc finger protein |
| Swissprots | E9PQF4 Q9BQA5 B4DWB4 Q96E65 Q9Y4M7 B3KPH6 |
| Accessions | EAW67460 EAW67461 EAW67462 EAW67463 Q9BQA5 AK056362 BAG51688 AK092869 AK300288 BAG62045 AK301452 BAG62976 AL080201 CAB45773 BC001073 AAH01073 BC001945 AAH01945 BC012856 AAH12856 BC017234 AAH17234 BF726036 BG821695 DC326345 DQ894647 ABM85573 XM_006718814 XP_006718877 XM_011542744 XP_011541046 XM_011542745 XP_011541047 XM_011542746 XP_011541048 NM_001243259 NP_001230188 NM_015517 NP_056332 NM_198971 NP_945322 |
| Function | Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:14752047, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:17163457, ECO:0000269|PubMed:17974976, ECO:0000269|PubMed:18850719}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:18850719}. Note=Associated with discrete nuclear foci. |
| Tissue Specificity | Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver. {ECO:0000269|PubMed:11553631}. |
HiNF-P CRISPR/Cas9 KO Plasmid (h) - sc-416760 from Santa Cruz Biotechnology
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HiNF-P HDR Plasmid (h) - sc-416760-HDR from Santa Cruz Biotechnology
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HiNF-P Double Nickase Plasmid (h) - sc-416760-NIC from Santa Cruz Biotechnology
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HiNF-P Double Nickase Plasmid (h2) - sc-416760-NIC-2 from Santa Cruz Biotechnology
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HiNF-P CRISPR Activation Plasmid (h) - sc-416760-ACT from Santa Cruz Biotechnology
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HiNF-P CRISPR Activation Plasmid (h2) - sc-416760-ACT-2 from Santa Cruz Biotechnology
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HiNF-P Lentiviral Activation Particles (h) - sc-416760-LAC from Santa Cruz Biotechnology
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HiNF-P Lentiviral Activation Particles (h2) - sc-416760-LAC-2 from Santa Cruz Biotechnology
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HiNF-P siRNA (h) - sc-60790 from Santa Cruz Biotechnology
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HiNF-P shRNA Plasmid (h) - sc-60790-SH from Santa Cruz Biotechnology
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HiNF-P shRNA (h) Lentiviral Particles - sc-60790-V from Santa Cruz Biotechnology
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HINFP RNAi - H00025988-R01 from Novus Biologicals
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MISSION® esiRNA - EHU010181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10038 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10038 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04550 from Sigma-Aldrich
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HINFP siRNA (Human) - CRH8636 from Cohesion Biosciences
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HINFP RNAi - H00025988-R02 from Novus Biologicals
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HINFP - MBS8205792 from MyBioSource
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shRNA set against Human HINFP (NM_198971.2) - SHH312213 from Creative biogene
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HINFP shRNA Plasmid (Human) - CHH8636 from Cohesion Biosciences
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HINFP miRNA 3'UTR clone - MiUTR3H-08962 from Creative biogene
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HINFP miRNA 3'UTR clone - MiUTR3H-08963 from Creative biogene
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