Gene Symbol | HINFP |
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Entrez Gene | 25988 |
Alt Symbol | HiNF-P, MIZF, ZNF743 |
Species | Human |
Gene Type | protein-coding |
Description | histone H4 transcription factor |
Other Description | MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein|MBD2-interacting zinc finger 1|MBD2-interacting zinc finger protein|histone H4 gene-specific protein HiNF-P|histone nuclear factor P|methyl-CpG-binding protein 2-interacting zinc finger protein |
Swissprots | E9PQF4 Q9BQA5 B4DWB4 Q96E65 Q9Y4M7 B3KPH6 |
Accessions | EAW67460 EAW67461 EAW67462 EAW67463 Q9BQA5 AK056362 BAG51688 AK092869 AK300288 BAG62045 AK301452 BAG62976 AL080201 CAB45773 BC001073 AAH01073 BC001945 AAH01945 BC012856 AAH12856 BC017234 AAH17234 BF726036 BG821695 DC326345 DQ894647 ABM85573 XM_006718814 XP_006718877 XM_011542744 XP_011541046 XM_011542745 XP_011541047 XM_011542746 XP_011541048 NM_001243259 NP_001230188 NM_015517 NP_056332 NM_198971 NP_945322 |
Function | Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:14752047, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:17163457, ECO:0000269|PubMed:17974976, ECO:0000269|PubMed:18850719}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11553631, ECO:0000269|PubMed:14585971, ECO:0000269|PubMed:15988025, ECO:0000269|PubMed:18850719}. Note=Associated with discrete nuclear foci. |
Tissue Specificity | Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver. {ECO:0000269|PubMed:11553631}. |
Human MBD2 Interacting Zinc Finger MIZF full length protein - ab161858 from Abcam
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Human MBD2 Interacting Zinc Finger MIZF protein fragment - ab161859 from Abcam
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HINFP Antibody Blocking Peptide - LS-E1813 from LifeSpan Bioscience
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HINFP Antibody Blocking Peptide - LS-E14136 from LifeSpan Bioscience
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HINFP Antibody Blocking Peptide - LS-E11421 from LifeSpan Bioscience
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Recombinant Human HINFP Protein - H00025988-P01 from Novus Biologicals
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Recombinant Human HINFP Protein - H00025988-Q01 from Novus Biologicals
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HINFP-Antibody-Center-Blocking-peptide - BP12622c from Abgent, a WuXi AppTec company
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MIZF - H00025988-P01-02 from Acris Antibodies
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MIZF - H00025988-Q01-10 from Acris Antibodies
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MIZF - H00025988-Q01-25 from Acris Antibodies
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HINFP fusion protein - Ag0115 from Proteintech Group
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Recombinant Human Histone H4 Transcription Factor, T7-tagged - HINFP-2942H from Creative Biomart
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Recombinant Human HINFP, GST-tagged - HINFP-13778H from Creative Biomart
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Recombinant Human HINFP - HINFP-829H from Creative Biomart
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Recombinant Human Histone H4 transcription factor(HINFP) - CSB-YP010361HU CSB-EP010361HU CSB-BP010361HU CSB-MP010361HU from Cusabio
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Troponin I-SS (14-64) - sc-4981 WB from Santa Cruz Biotechnology
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HINFP Protein - abx164018 from Abbexa
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MIZF (transcript variant 1) - TP300864 from Acris Antibodies
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HINFP Recombinant Protein Antigen - NBP2-32582PEP from Novus Biologicals
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HINFP Peptide, Human - M34GP06995H from Creative Peptides
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Histone H4 transcription factor (HINFP), Recombinant Protein - MBS1358411 from MyBioSource
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HINFP Recombinant Protein Antigen - NBP2-56798PEP from Novus Biologicals
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