PRDM5

Gene Symbol PRDM5
Entrez Gene 11107
Alt Symbol BCS2, PFM2
Species Human
Gene Type protein-coding
Description PR domain containing 5
Other Description PR domain zinc finger protein 5
Swissprots Q9NQX1 Q0VAI9 Q0VAJ0 Q6NXQ7
Accessions CCO13795 EAX05267 EAX05268 EAX05269 Q9NQX1 AF272897 AAF78077 AK056352 BAG51686 AK310958 AK314293 AW341546 BC047115 BC066942 AAH66942 BC121037 AAI21038 BC121038 AAI21039 BM563688 BX646150 XM_005262708 XP_005262765 XM_011531562 XP_011529864 XM_011531563 XP_011529865 XM_011531564 XP_011529866 XM_011531565 XP_011529867 XM_011531566 XP_011529868 XM_011531567 XP_011529869 XM_011531568 XP_011529870 XM_011531569 XP_011529871 XM_011531570 XP_011529872 XR_938677 XR_938678 XR_938679 XR_938680 NM_001300823 NP_001287752 NM_001300824 NP_001287753 NM_018699 NP_061169
Function Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019, ECO:0000269|PubMed:21664999}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019}.
Tissue Specificity Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17699856}.

Human PRDM5 full length protein - ab131922 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab131922 stained with Coomassie Blue.

Human PRDM5 peptide - ab23001 from Abcam

Category Peptide
Species Human

PRDM5 Antibody Blocking Peptide - LS-E4911 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PRDM5 Antibody Blocking Peptide - LS-E14221 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PRDM5 Antibody Blocking Peptide - LS-E11558 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PRDM5 Recombinant Protein - H00011107-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

PRDM5-Antibody-N-term-Blocking-Peptide - BP17297a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PRDM5 / PFM2 - H00011107-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PRDM5 / PFM2 - H00011107-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PRDM5 fusion protein - Ag5277 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PRDM5 fusion protein - ag5376 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human PRDM5, GST-tagged - PRDM5-1937H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human PR domain zinc finger protein 5(PRDM5) - CSB-YP868292HU CSB-EP868292HU CSB-BP868292HU CSB-MP868292HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PRDM5 Protein - abx164327 from Abbexa

Category Protein
Species Human, Mouse, Rat

PR domain zinc finger protein 5 (PRDM5), Recombinant Protein - MBS1415633 from MyBioSource

Category Protein
Prices $1,425.00, $1,425.00, $1,655.00, $1,655.00, $2,415.00, $2,415.00, $2,860.00, $2,860.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PRDM5 Recombinant Protein Antigen - NBP2-13810PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Recombinant PRDM5 protein - 31494 from ActiveMotif

Category Protein
Prices $395.00
Sizes 20 µg
Source Baculovirus
Species Human
Recombinant PRDM5 protein gel PRDM5 protein was run on an 8% SDS-PAGE gel and stained with Coomassie blue.

PRDM5-PFM2-Antibody-Blocking-peptide - BP1205a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PRDM5 Peptide, Human - M34GP12354H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
Search more