PRDM5

Gene Symbol PRDM5
Entrez Gene 11107
Alt Symbol BCS2, PFM2
Species Human
Gene Type protein-coding
Description PR domain containing 5
Other Description PR domain zinc finger protein 5
Swissprots Q9NQX1 Q0VAI9 Q0VAJ0 Q6NXQ7
Accessions CCO13795 EAX05267 EAX05268 EAX05269 Q9NQX1 AF272897 AAF78077 AK056352 BAG51686 AK310958 AK314293 AW341546 BC047115 BC066942 AAH66942 BC121037 AAI21038 BC121038 AAI21039 BM563688 BX646150 XM_005262708 XP_005262765 XM_011531562 XP_011529864 XM_011531563 XP_011529865 XM_011531564 XP_011529866 XM_011531565 XP_011529867 XM_011531566 XP_011529868 XM_011531567 XP_011529869 XM_011531568 XP_011529870 XM_011531569 XP_011529871 XM_011531570 XP_011529872 XR_938677 XR_938678 XR_938679 XR_938680 NM_001300823 NP_001287752 NM_001300824 NP_001287753 NM_018699 NP_061169
Function Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019, ECO:0000269|PubMed:21664999}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019}.
Tissue Specificity Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17699856}.

PRDM5 CRISPR/Cas9 KO Plasmid (h) - sc-408823 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 HDR Plasmid (h) - sc-408823-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 Double Nickase Plasmid (h) - sc-408823-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 Double Nickase Plasmid (h2) - sc-408823-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 CRISPR Activation Plasmid (h) - sc-408823-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 CRISPR Activation Plasmid (h2) - sc-408823-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 Lentiviral Activation Particles (h) - sc-408823-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 Lentiviral Activation Particles (h2) - sc-408823-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRDM5 siRNA (h) - sc-61397 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM5 shRNA Plasmid (h) - sc-61397-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM5 shRNA (h) Lentiviral Particles - sc-61397-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRDM5 RNAi - H00011107-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17377 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17377 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02816 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02816

PRDM5 siRNA (Human) - CRH7598 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRDM5 (NM_018699.2) - SHH382248 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PRDM5(NM_018699.2) - SHR137850 from Creative biogene

Category siRNA
Species Reactivities Human

PRDM5 shRNA Plasmid (Human) - CHH7598 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRDM5 miRNA 3'UTR clone - MiUTR1H-08230 from Creative biogene

Species Reactivities Human
Search more