PRDM5

Gene Symbol PRDM5
Entrez Gene 11107
Alt Symbol BCS2, PFM2
Species Human
Gene Type protein-coding
Description PR domain containing 5
Other Description PR domain zinc finger protein 5
Swissprots Q9NQX1 Q0VAI9 Q0VAJ0 Q6NXQ7
Accessions CCO13795 EAX05267 EAX05268 EAX05269 Q9NQX1 AF272897 AAF78077 AK056352 BAG51686 AK310958 AK314293 AW341546 BC047115 BC066942 AAH66942 BC121037 AAI21038 BC121038 AAI21039 BM563688 BX646150 XM_005262708 XP_005262765 XM_011531562 XP_011529864 XM_011531563 XP_011529865 XM_011531564 XP_011529866 XM_011531565 XP_011529867 XM_011531566 XP_011529868 XM_011531567 XP_011529869 XM_011531568 XP_011529870 XM_011531569 XP_011529871 XM_011531570 XP_011529872 XR_938677 XR_938678 XR_938679 XR_938680 NM_001300823 NP_001287752 NM_001300824 NP_001287753 NM_018699 NP_061169
Function Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019, ECO:0000269|PubMed:21664999}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019}.
Tissue Specificity Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17699856}.

PRDM5 (A-12) - sc-376277 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRDM5 (A-12): sc-376277. Western blot analysis of PRDM5 expression in HL-60 (A) and HuT 78 (B) whole cell lysates.

PRDM5 (C-15) - sc-48654 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRDM5 (C-15): sc-48654. Western blot analysis of PRDM5 expression in ES-2 (A), HuT 78 (B), HL-60 (C), OV-90 (D) and SW480 (E) whole cell lysates.

PRDM5 (C-12) - sc-48653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRDM5 (C-12): sc-48653. Western blot analysis of PRDM5 expression in NIH/3T3 nuclear extract.

PRDM5 (H-300) - sc-98881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRDM5 (H-300): sc-98881. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear and cytoplasmic localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

PRDM5 (N-15) - sc-48655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRDM5 (N-15): sc-48655. Western blot analysis of PRDM5 expression in NIH/3T3 nuclear extract.

PRDM5 (N-18) - sc-48656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRDM5 (N-18): sc-48656. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing nuclear staining of glandular cells.

Anti-PRDM5 antibody - ab84572 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PRDM5 antibody (ab84572) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PRDM5 antibody - ab79016 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab79016, at 5 µg/ml, staining PRDM5 in formalin-fixed, paraffin-embedded human colon tissue by Immunohistochemistry.

Anti-PRDM5 antibody - ab130605 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PRDM5 antibody (ab130605) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-PRDM5 antibody - ab47066 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PRDM5 antibody (ab47066) at 1 µg/ml + HL60 cell lysate.

Anti-PRDM5 Antibody (aa387-404) - LS-C148879 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, AP) - LS-C267069 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, APC) - LS-C267070 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, FITC) - LS-C267071 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, Biotin) - LS-C267072 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, Azide-free, HRP) - LS-C267073 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160, PE) - LS-C267074 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (aa131-160) - LS-C324278 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM5 Antibody (C-Terminus) - LS-C110377 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRDM5 antibody LS-C110377 Western blot of 293T cell lysate.

Anti-PRDM5 Antibody (aa21-70) - LS-C201362 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human ACHN. PRDM5 antibody dilution 1.0 ug/ml.

Anti-PRDM5 Antibody (aa132-160) - LS-C158728 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PRDM5 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PRDM5 antibody detected the PRDM5 protein (arrow).

Anti-PRDM5 Antibody (aa36-85) IHC-plus™ - LS-B3500 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PRDM5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3500 concentration 5 ug/ml.

Anti-PRDM5 Antibody (aa100-200) IHC-plus™ - LS-B1982 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PRDM5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1982 concentration 5 ug/ml.

PRDM5 Antibody - NB100-56419 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PRDM5 Antibody [NB100-56419] - analysis of PRDM5 in HL60 cell lysate using this antibody.

PRDM5 Antibody - NBP2-13810 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PRDM5 Antibody [NBP2-13810] - Staining of human cell line RH-30 shows localization to nucleus, nucleoli & nuclear bodies.
Search more