TRIM71

Gene Symbol TRIM71
Entrez Gene 131405
Alt Symbol LIN-41, LIN41
Species Human
Gene Type protein-coding
Description tripartite motif containing 71, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase TRIM71|abnormal cell LINeage LIN-41|homolog of C. elegans Lin-41|protein lin-41 homolog|tripartite motif-containing 71|tripartite motif-containing protein 71
Swissprots Q2Q1W2
Accessions Q2Q1W2 BC156152 AAI56153 BC157052 AAI57053 DQ232881 ABB18374 NM_001039111 NP_001034200
Function E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, P-body {ECO:0000250}.
Tissue Specificity Specifically expressed in testis. {ECO:0000269|PubMed:15722555}.
Top Pathways MicroRNAs in cancer

LIN-41 CRISPR/Cas9 KO Plasmid (h) - sc-405036 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 HDR Plasmid (h) - sc-405036-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 Double Nickase Plasmid (h) - sc-405036-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 Double Nickase Plasmid (h2) - sc-405036-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 CRISPR Activation Plasmid (h) - sc-405036-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 CRISPR Activation Plasmid (h2) - sc-405036-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 Lentiviral Activation Particles (h) - sc-405036-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 Lentiviral Activation Particles (h2) - sc-405036-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LIN-41 siRNA (h) - sc-72328 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIN-41 shRNA Plasmid (h) - sc-72328-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LIN-41 shRNA (h) Lentiviral Particles - sc-72328-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN22015 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22015 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TRIM71 siRNA (Human) - CRJ5062 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRIM71 - MBS8233992 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRIM71 (NM_001039111.1) - SHH435068 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TRIM71(NM_001039111.1) - SHL095102 from Creative biogene

Category siRNA
Species Reactivities Human

TRIM71 shRNA Plasmid (Human) - CHJ5062 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRIM71 miRNA 3'UTR clone - MiUTR1H-10760 from Creative biogene

Species Reactivities Human
Search more