TRIM71

Gene Symbol TRIM71
Entrez Gene 131405
Alt Symbol LIN-41, LIN41
Species Human
Gene Type protein-coding
Description tripartite motif containing 71, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase TRIM71|abnormal cell LINeage LIN-41|homolog of C. elegans Lin-41|protein lin-41 homolog|tripartite motif-containing 71|tripartite motif-containing protein 71
Swissprots Q2Q1W2
Accessions Q2Q1W2 BC156152 AAI56153 BC157052 AAI57053 DQ232881 ABB18374 NM_001039111 NP_001034200
Function E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, P-body {ECO:0000250}.
Tissue Specificity Specifically expressed in testis. {ECO:0000269|PubMed:15722555}.
Top Pathways MicroRNAs in cancer

LIN-41 (B-12) - sc-393338 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIN-41 (B-12): sc-393338. Western blot analysis of LIN-41 expression in NTERA-2 cl.D1 whole cell lysate.

LIN-41 (C-16) - sc-54033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LIN-41 (E-1) - sc-393352 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIN-41 (E-1): sc-393352. Western blot analysis of LIN-41 expression in NTERA-2 cl.D1 whole cell lysate (A) and human testis tissue extract (B).

LIN-41 (H-269) - sc-134793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIN-41 (H-269): sc-134793. Western blot analysis of LIN-41 expression in A-10 whole cell lysate.

LIN-41 (Q-17) - sc-54036 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIN-41 (Q-17): sc-54036. Western blot analysis of LIN-41 expression in mouse brain tissue extract.

LIN-41 (G-17) - sc-54034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIN-41 (G-17): sc-54034. Western blot analysis of LIN-41 expression in mouse brain tissue extract.

LIN-41 (P-18) - sc-54035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIN-41 (P-18): sc-54035. Western blot analysis of LIN-41 expression in F9 whole cell lysate.

Anti-TRIM71 antibody - ab105330 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-TRIM71 antibody (ab105330) at 1 µg/mlLane 2 : Anti-TRIM71 antibody (ab105330) at 2 µg/mlLane 1 : Human brain tissue lysate Lane 2 : Human brain tissue lysate Lysates/proteins at 15 µg per lane.SecondaryAnti-rabbit secondary antibody

Anti-TRIM71 antibody - ab117607 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab117607, at 3.75 µg/ml, staining TRIM71 in Formalin-fixed, Paraffin-embedded Human Brain Cerebellum tissue by Immunohistochemistry.

Anti-TRIM71 antibody - ab124330 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TRIM71 antibody (ab124330) at 1/1000 dilutionLane 1 : Human fetal brain lysateLane 2 : Human fetal kidney lysateLane 3 : Human fetal heart lysate

Anti-TRIM71 antibody - ab176898 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TRIM71 antibody (ab176898) at 1/500 dilution + Human liver lysatedeveloped using the ECL technique

Anti-LIN41 / TRIM71 Antibody - LS-C153174 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIN41 / TRIM71 Antibody - LS-C183468 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIN41 / TRIM71 Antibody (aa409-419) - LS-C112949 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TRIM71 antibody (0.5 ug/ml) staining of NIH3T3 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-LIN41 / TRIM71 Antibody (C-Terminus) - LS-C115887 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of TRIM71 in Human Brain cells with TRIM71 antibody at 20 ug/ml.

Anti-LIN41 / TRIM71 Antibody (N-Terminus) - LS-C178928 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LIN41 / TRIM71 Antibody (aa390-402) IHC-plus™ - LS-B5240 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TRIM71 antibody IHC of human brain cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5240 concentration 3.75 ug/ml.

LIN-41/TRIM71 Antibody [Unconjugated] - AF5104 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of BG0IV human embryonic stem cells and NTera‑2 human testicular embryonic carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human LIN‑41 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5104) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for LIN‑41 at approximately 95 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

LIN-41/TRIM71 Antibody - NBP1-81306 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: LIN-41/TRIM71 Antibody [NBP1-81306] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

LIN-41/TRIM71 Antibody - NBP2-34043 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: TRIM71/lin-41 Antibody [NBP2-34043] - Staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.

LIN-41/TRIM71 Antibody - NBP2-27490 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

LIN-41/TRIM71 Antibody - NBP1-76281 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LIN-41/TRIM71 Antibody - NBP2-27491 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: LIN-41/TRIM71 Antibody [NBP2-27491] - Analysis of TRIM71/lin-41 in NIH3T3 lysate (35ug protein in RIPA buffer) using NBP2-27491 at 0.5ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TRIM71 antibody produced in goat - SAB2501385 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TRIM71 <B>Cat. No. SAB2501385</B>: (0.5 μg/mL) staining of HEK293 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TRIM71 antibody produced in goat - SAB2501386 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TRIM71 <B>Cat. No. SAB2501386</B>: (0.5 μg/mL) staining of NIH3T3 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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