TRIM13

Gene Symbol TRIM13
Entrez Gene 10206
Alt Symbol CAR, DLEU5, LEU5, RFP2, RNF77
Species Human
Gene Type protein-coding
Description tripartite motif containing 13
Other Description B-cell chronic lymphocytic leukemia tumor suppressor Leu5|CLL-associated RING finger|E3 ubiquitin-protein ligase TRIM13|RING finger protein 77|leukemia-associated protein 5|putative tumor suppressor RFP2|ret finger protein 2|tripartite motif protein 13|tripartite motif-containing 13|tripartite motif-containing protein 13
Swissprots B2RB49 Q5UBW0 Q5W0U9 Q9BQ47 Q5W0U8 O60858 Q9C021
Accessions AAK13059 AAK51624 CBH19816 CCQ43336 EAX08844 EAX08845 EAX08846 EAX08847 EAX08848 O60858 AF220127 AAG53500 AF220128 AAG53501 AF241850 AAF91315 AJ224819 CAA12136 AK001806 AK056841 AK314496 BAG37096 AL360196 AL832695 CAD38633 AY191002 AAO38979 AY455758 AAR31110 AY764035 AAV51406 BC003579 AAH03579 BC029514 BC055420 BC063407 AAH63407 BI668033 DQ892570 ABM83496 DQ895785 ABM86711 NM_001007278 NP_001007279 NM_005798 NP_005789 NM_052811 NP_434698 NM_213590 NP_998755
Function E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor. {ECO:0000269|PubMed:17314412, ECO:0000269|PubMed:21333377, ECO:0000269|PubMed:22178386}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:17314412, ECO:0000269|PubMed:21333377, ECO:0000269|PubMed:22178386}; Single-pass membrane protein {ECO:0000269|PubMed:17314412, ECO:0000269|PubMed:21333377, ECO:0000269|PubMed:22178386}. Note=Concentrates and colocalizes with p62/SQSTM1 and ZFYVE1 at the perinuclear endoplasmic reticulum.

Human-TRIM13-cDNA-Clone - DC01336 from Abgent, a WuXi AppTec company

Prices $549.45
Sizes 10 µg
Species Human
Accession BC003579

TRIM13 - MBS1276765 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC003579

Human TRIM13 cDNA clone(NM_052811.2) - CDFG005720 from Creative Biomart

Species Human
Accession NM_052811.2

Human TRIM13 cDNA clone(NM_213590.1) - CDFG013939 from Creative Biomart

Species Human
Accession NM_213590.1

Human TRIM13 cDNA clone(NM_001007278.1) - CDFH020305 from Creative Biomart

Species Human
Accession NM_001007278.1

Human TRIM13 cDNA clone(NM_005798.3) - CDFH020306 from Creative Biomart

Species Human
Accession NM_005798.3

Human TRIM13 cDNA clone(NM_005798.3) - CDFH020307 from Creative Biomart

Species Human
Accession NM_005798.3

human TRIM13 ORF clone - CDCH094826 from Creative Biomart

Species Human
Accession NM_001007278

human TRIM13 ORF clone - CDCH094827 from Creative Biomart

Species Human
Accession NM_001007278

human TRIM13 ORF clone - CDCH094828 from Creative Biomart

Species Human
Accession NM_001007278

human TRIM13 ORF clone - CDCH094829 from Creative Biomart

Species Human
Accession NM_001007278

human TRIM13 ORF clone - CDCH094830 from Creative Biomart

Species Human
Accession NM_001007278

human TRIM13 ORF clone - CDCH094831 from Creative Biomart

Species Human
Accession NM_001007278

Human TRIM13 ORF Clone(NM_005798.3) - CDCL179588 from Creative Biomart

Species Human
Accession NM_005798.3

Human TRIM13 ORF Clone(NM_005798.3) - CDCR291331 from Creative Biomart

Species Human
Accession NM_005798.3

Human TRIM13 ORF Clone(NM_005798.3) - CDCR291332 from Creative Biomart

Species Human
Accession NM_005798.3

Human TRIM13 ORF Clone(NM_052811.2) - CDCR314157 from Creative Biomart

Species Human
Accession NM_052811.2

Human TRIM13 ORF Clone(NM_052811.2) - CDCR314159 from Creative Biomart

Species Human
Accession NM_052811.2

Human TRIM13 ORF Clone(NM_213590.1) - CDCR328290 from Creative Biomart

Species Human
Accession NM_213590.1

Human TRIM13 ORF Clone(NM_213590.1) - CDCR328291 from Creative Biomart

Species Human
Accession NM_213590.1

Human TRIM13 ORF Clone(NM_001007278.1) - CDCR340101 from Creative Biomart

Species Human
Accession NM_001007278.1

Human TRIM13 ORF Clone(NM_001007278.1) - CDCR340260 from Creative Biomart

Species Human
Accession NM_001007278.1

Human TRIM13 ORF Clone(NM_005798.3) - CDCR291331 from Creative biogene

Species Human

Human TRIM13 ORF Clone(NM_213590.1) - CDCR328290 from Creative biogene

Species Human
Search more