Gene Symbol | POU2AF1 |
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Entrez Gene | 5450 |
Alt Symbol | BOB1, OBF-1, OBF1, OCAB |
Species | Human |
Gene Type | protein-coding |
Description | POU class 2 associating factor 1 |
Other Description | B-cell-specific coactivator OBF-1|BOB-1|OCA-B|OCT-binding factor 1|POU domain class 2-associating factor 1|POU domain, class 2, associating factor 1 |
Swissprots | Q14983 B2R8Z9 Q16633 |
Accessions | AAB34937 CBX47639 EAW67137 Q16633 AK313573 BAG36346 BC032549 AAH32549 DQ890869 ABM81795 EU176491 ABW03292 X83504 CAA58494 Z47550 CAA87630 Z49194 CAA89053 XM_005271593 XP_005271650 XM_005271594 XP_005271651 XM_006718859 XP_006718922 XM_006718860 XP_006718923 NM_006235 NP_006226 |
Function | Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. |
Subcellular Location | Nucleus. |
Tissue Specificity | B-cell specific. |
Human BOB1 full length protein - ab109849 from Abcam
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Human BOB1 peptide - ab22946 from Abcam
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POU2AF1 / BOB1 Antibody Blocking Peptide - LS-E25439 from LifeSpan Bioscience
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POU2AF1 / BOB1 Antibody Blocking Peptide - LS-E27354 from LifeSpan Bioscience
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POU2AF1 / BOB1 Antibody Blocking Peptide - LS-E9938 from LifeSpan Bioscience
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BOB1 Partial Recombinant Protein - H00005450-Q01 from Novus Biologicals
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Recombinant Human BOB1 Protein - NBP1-72368 from Novus Biologicals
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BOB1 Recombinant Protein - P3717 from Novus Biologicals
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POU2AF1-Antibody-N-term-Blocking-Peptide - BP9096a from Abgent, a WuXi AppTec company
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BOB1 blocking peptide - GTX89896-PEP from GeneTex
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Recombinant human POU domain class 2-associating factor 1 (OPCA00289) - OPCA00289 from Aviva Systems Biology
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Human POU2AF1 protein - orb244814 from Biorbyt
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Human POU2AF1 protein - orb169057 from Biorbyt
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BOB-1 peptide - orb72404 from Biorbyt
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POU2AF1 Immunizing peptide - orb17414 from Biorbyt
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POU2AF1 protein (His tag) - 80R-1880 from Fitzgerald
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BOB1 Peptide - AC21-0267-P from Abcore
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BOB1 Peptide - AC21-2179-P from Abcore
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BOB1 Peptide - AC21-2180-P from Abcore
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POU2AF1 / BOB1 (1-256, His-tag) - AR39062PU-L from Acris Antibodies
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POU2AF1 / BOB1 (1-256, His-tag) - AR39062PU-N from Acris Antibodies
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POU2AF1 / BOB1 - H00005450-Q01-10 from Acris Antibodies
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POU2AF1 / BOB1 - H00005450-Q01-25 from Acris Antibodies
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POU2AF1 / BOB1 - P3717 from Acris Antibodies
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POU2AF1, 1-256aa, Human, His tag, E.coli - 01-P1122 from ARP American Research Products
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