FLVCR1

Gene Symbol	FLVCR1
Entrez Gene	28982
Alt Symbol	AXPC1, FLVCR, MFSD7B, PCA, PCARP
Species	Human
Gene Type	protein-coding
Description	feline leukemia virus subgroup C cellular receptor 1
Other Description	feline leukemia virus subgroup C receptor-related protein 1
Swissprots	Q9NVR9 Q9Y5Y0 Q1HE16 Q86XY9
Accessions	ABF47096 EAW93374 Q9Y5Y0 AF118637 AAD45243 AK001419 BAA91679 AK090739 AK314481 BAG37085 BC048312 AAH48312 BE088852 BY800024 GD138340 XM_011509446 XP_011507748 XM_011509447 XP_011507749 XM_011509448 XP_011507750 XR_247024 XR_426771 XR_426772 XR_921769 NM_014053 NP_054772
Function	Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro. Required during erythtopoiesis to maintain intracellular free heme balance since in proerythroblasts, heme synthesis intensifies and it's accumulation is toxic for cells.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity	Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney. {ECO:0000269|PubMed:10400745}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FLVCR peptide (543-555) - ab45649 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

Human FLVCR full length protein - ab132323 from Abcam Category Protein Source Wheat germ Species Human

Human FLVCR peptide - ab86189 from Abcam Category Peptide

Human FLVCR protein fragment - ab162194 from Abcam Category Protein Source Wheat germ Species Human

FLVCR / FLVCR1 Antibody Blocking Peptide - LS-E25797 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FLVCR Protein - H00028982-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FLVCR Protein - H00028982-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FLVCR blocking peptide - GTX89644-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

FLVCR1 Immunizing peptide - orb17896 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Mfsd7b Blocking Peptide - 33R-3473 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FLVCR Peptide - AC21-0628-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FLVCR1 - H00028982-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FLVCR1 - H00028982-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FLVCR1 - H00028982-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FLVCR1 - H00028982-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FLVCR Peptide - 45-598P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

FLVCR1 fusion protein - ag12851 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

FLVCR, Peptide - MBS426262 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

FLVCR Recombinant Protein Antigen - NBP2-14019PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FLVCR1 Peptide, Human - M34GP05789H from Creative Peptides Category Peptide Source Synthetic. Species Human

FLVCR1 fusion protein - Ag25237 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

FLVCR1 fusion protein - Ag25220 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Search more