Gene Symbol | NGF |
---|---|
Entrez Gene | 4803 |
Alt Symbol | Beta-NGF, HSAN5, NGFB |
Species | Human |
Gene Type | protein-coding |
Description | nerve growth factor (beta polypeptide) |
Other Description | beta-nerve growth factor|nerve growth factor, beta subunit |
Swissprots | Q9P2Q8 P01138 Q9UKL8 Q96P60 A1A4E5 Q6FHA0 |
Accessions | AAA59931 AAD55975 BAA90437 CAA24755 EAW56629 P01138 AF411526 AAL05874 BC032517 AAH32517 BC126148 AAI26149 BC126150 AAI26151 BE045524 BT019733 AAV38538 CR541855 CAG46653 HQ258125 ADR82879 X52599 CAA36832 XM_006710663 XP_006710726 XM_006710665 XP_006710728 XM_011541518 XP_011539820 NM_002506 NP_002497 |
Function | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}. |
Subcellular Location | Secreted. |
Top Pathways | Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Inflammatory mediator regulation of TRP channels |
Active human NGF full length protein - ab105059 from Abcam
|
||||||||||
Active human NGF full length protein - ab179616 from Abcam
|
||||||||||
Active human NGF full length protein - ab84059 from Abcam
|
||||||||||
Active mouse NGF full length protein - ab123841 from Abcam
|
||||||||||
Active mouse NGF full length protein - ab69757 from Abcam
|
||||||||||
Active NGF full length protein - ab9796 from Abcam
|
||||||||||
Human NGF full length protein - ab138794 from Abcam
|
||||||||||
Human NGF full length protein - ab55441 from Abcam
|
||||||||||
Human NGF peptide - ab66458 from Abcam
|
||||||||||
Mouse NGF protein fragment - ab50125 from Abcam
|
||||||||||
NGF peptide - ab154297 from Abcam
|
||||||||||
NGF Antibody Blocking Peptide - LS-E9250 from LifeSpan Bioscience
|
||||||||||
Human beta-NGF Biologically Active Protein - NBP2-36437 from Novus Biologicals
|
||||||||||
beta-NGF Partial Recombinant Protein - H00004803-Q01 from Novus Biologicals
|
||||||||||
beta-NGF Protein - NBP1-43177 from Novus Biologicals
|
||||||||||
beta-NGF Recombinant Protein - P4017 from Novus Biologicals
|
||||||||||
beta-NGF Recombinant Protein - P3657 from Novus Biologicals
|
||||||||||
beta-NGF Recombinant Protein - P4432 from Novus Biologicals
|
||||||||||
beta-NGF Protein - NBP1-99302 from Novus Biologicals
|
||||||||||
Recombinant Human beta-NGF Protein - NBP1-99534 from Novus Biologicals
|
||||||||||
beta-NGF Protein - NBP1-99691 from Novus Biologicals
|
||||||||||
beta-NGF Protein - NBP2-26526 from Novus Biologicals
|
||||||||||
NGFB-Antibody-C-term-Blocking-peptide - BP11545b from Abgent, a WuXi AppTec company
|
||||||||||
NGFB-Antibody-Center-Blocking-Peptide - BP7771c from Abgent, a WuXi AppTec company
|
||||||||||
NGF beta protein - GTX29796 from GeneTex
|