NGF

Gene Symbol NGF
Entrez Gene 4803
Alt Symbol Beta-NGF, HSAN5, NGFB
Species Human
Gene Type protein-coding
Description nerve growth factor (beta polypeptide)
Other Description beta-nerve growth factor|nerve growth factor, beta subunit
Swissprots Q9P2Q8 P01138 Q9UKL8 Q96P60 A1A4E5 Q6FHA0
Accessions AAA59931 AAD55975 BAA90437 CAA24755 EAW56629 P01138 AF411526 AAL05874 BC032517 AAH32517 BC126148 AAI26149 BC126150 AAI26151 BE045524 BT019733 AAV38538 CR541855 CAG46653 HQ258125 ADR82879 X52599 CAA36832 XM_006710663 XP_006710726 XM_006710665 XP_006710728 XM_011541518 XP_011539820 NM_002506 NP_002497
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
Subcellular Location Secreted.
Top Pathways Apoptosis, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Inflammatory mediator regulation of TRP channels

NGF Antibody - 2046 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of various concentrations of recombinant human NGF protein using NGF Antibody.

NGF (E-12) - sc-365944 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NGF (E-12): sc-365944. Western blot analysis of NGF expression in mouse brain tissue extract.

NGF (D-19) - sc-33901 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NGF (FL-241) - sc-33602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NGF (FL-241): sc-33602. Western blot analysis of NGF expression in mouse brain tissue extract .

NGF (G-14) - sc-33899 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NGF (H-20) - sc-548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of 10 ng each of NGF (A), BDNF (B), NT-3 (C) and NT-4 (D) purified proteins. Antibodies tested include NGF (H-20): sc-548 (I), NGF (M-20): sc-549 (II), BDNF (N-20): sc-546 (III) and NT-4 (N-20): sc-545 (IV).

NGF (M-20) - sc-549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of 10 ng each of NGF (A), BDNF (B), NT-3 (C) and NT-4 (D) purified proteins. Antibodies tested include NGF (H-20): sc-548 (I), NGF (M-20): sc-549 (II), BDNF (N-20): sc-546 (III) and NT-4 (N-20): sc-545 (IV).

Anti-NGF antibody - ab6199 from Abcam

Prices $400.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
ab6199 at a 1/500 dilution staining rat brain tissue sections by Immunohistochemistry (Formalin-fixed paraffin-embedded sections). The tissue section was paraformaldehyde fixed and blocked with 2% BSA prior to incubation with the antibody for 24 hours. Bound antibody was detected using a biotinylated goat anti-rabbit IgG antibody. This image is courtesy of an Abreview submitted by Grazyna Niewiadomska.See Abreview

Anti-NGF antibody - ab6198 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab6198 at 1/1000 staining perfusion fixed rat brain tissue sections by IHC-Fr. The animals were pre-perfused with Tris buffer pH 10, followed by 4% paraformadehyde and 15% of a saturated solution of picric acid. The brains were post-fixed in the same fixative overnight, cryoprotected in 20% sucrose for 24 hours, frozen and cut with a cryostat. Free floating immunostaining was performed. An Alexa-Fluor ® 488 conjugated goat anti-rabbit antibody was used as the secondary.The image shows the staining obtained with this antibody using direct fluorescence in rat cortical neurons, with two different magnifications of acquisition (X10 and X20).See Abreview

Anti-NGF antibody - ab49205 from Abcam

Prices $373.00
Sizes 500 µl
Host Sheep
Clonality Polyclonal

Anti-NGF antibody - ab66459 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NGF antibody (ab66459) at 1 µg/mlLane 1 : Lung (Human) Tissue Lysate - adult normal tissueLane 2 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 3 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-NGF antibody - ab64136 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-NGF antibody - ab10515 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NGF antibody - ab28974 from Abcam

Prices $370.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal

Anti-NGF antibody - ab80014 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of NGF in formalin-fixed, paraffin-embedded human brain tissue using ab80014 at 1/10 dilution, followed by a peroxidase-conjugated secondary antibody and DAB staining.

Anti-NGF antibody - ab9795 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NGF antibody [25623.1] - ab10513 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 25623.1

Anti-NGF antibody [AS21] - ab16161 from Abcam

Prices $370.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone AS21

Anti-NGF antibody [EP1318Y] - ab68151 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1318Y
Overlay histogram showing SH-SY5Y cells stained with ab68151 (red line) at 1/280 dilution. The cells were fixed with 2% paraformaldehyde. The secondary antibody used was a FITC conjugated goat anti-rabbit IgG at 1/150 dilution. Isotype control antibody (black line) was rabbit monoclonal IgG used under the same conditions. Cells also incubated without primary antibody and secondary antibody (blue line)

Anti-NGF antibody [EP1320Y] - ab52918 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1320Y
All lanes : Anti-NGF antibody [EP1320Y] (ab52918) at 1/1000 dilution (purified)Lane 1 : Human fetal brain lysateLane 2 : Human fetal thymus lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryHRP conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-NGF antibody [EP1320Y] (HRP) - ab195536 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1320Y
IHC image of NGF staining in a section of formalin-fixed paraffin-embedded normal human cerebellum, performed on a Leica BOND. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20mins. The section was then incubated with ab195536, 1/100 dilution, for 15 mins at room temperature. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. The inset negative control image is taken from an identical assay without primary antibody.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-NGF antibody - BSA and Azide free - ab24486 from Abcam

Prices $372.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

Anti-NGF Antibody - LS-C73299 from LifeSpan Bioscience

Prices $415.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-NGF Antibody - LS-C94335 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-NGF Antibody - LS-C94330 from LifeSpan Bioscience

Prices $325.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal
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