SMARCA2

Gene Symbol	SMARCA2
Entrez Gene	6595
Alt Symbol	BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Species	Human
Gene Type	protein-coding
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Other Description	ATP-dependent helicase SMARCA2|BAF190B|BRG1-associated factor 190B|SNF2-alpha|SNF2/SWI2-like protein 2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2|global transcription activator homologous sequence|probable global transcription activator SNF2L2|protein brahma homolog|sucrose nonfermenting 2-like protein 2
Swissprots	B1ALG4 D3DRH4 B1ALG3 D3DRH5 P51531
Accessions	AAB68685 EAW58811 EAW58812 EAW58813 EAW58814 EAW58815 P51531 AK094076 BAC04280 AK296373 BAG59047 AK298045 BAG60343 AK299683 BAG61590 AK300093 BAG61895 AK308941 AL558829 AY293824 BC040029 AAH40029 BC068252 BC156185 AAI56186 BI758293 BM921013 CA313181 CD107405 CD513892 CD702931 DA084762 DA823500 X72889 CAA51407 NM_001289396 NP_001276325 NM_001289397 NP_001276326 NM_001289398 NP_001276327 NM_001289399 NP_001276328 NM_001289400 NP_001276329 NM_003070 NP_003061 NM_139045 NP_620614
Function	Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMARCA2 / BRM protein fragment - ab159542 from Abcam Category Protein Source Wheat germ Species Human

Human SMARCA2 / BRM protein fragment - ab198121 from Abcam Category Protein Source E. coli Species Human

Human SMARCA2 / BRM protein fragment - ab176945 from Abcam Category Protein Source E. coli Species Human

Recombinant Human BRM Protein - H00006595-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human SMARCA2 protein - orb244546 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human SMARCA2 protein - orb245994 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

SMARCA2 Blocking Peptide - 33R-9606 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BRM Blocking Peptide - abx063277 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Monkey

SMARCA2 / BRM - H00006595-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SMARCA2 / BRM - H00006595-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SMARCA2 fusion protein - ag8127 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SMARCA2 fusion protein - Ag6638 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant SMARCA2 / BRM (1367-1511) protein - 31449 from ActiveMotif Category Protein Prices $395.00 Sizes 100 μg Source E. coli Species Human

Recombinant SMARCA2 / BRM (1367-1511), GST-tag - 31481 from ActiveMotif Prices $395.00 Sizes 100 µg Source E. coli Species Human

Recombinant Human SMARCA2, GST-tagged - SMARCA2-159H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human SMARCA2, His&FLAG-tagged - SMARCA2-71H from Creative Biomart Category Protein Source E. coli Species Human

BRM Blocking Peptide - CBP2083 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey

BRM Peptide - BS5631P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant human Probable global transcription activator SNF2L2 - CSB-YP021799HU CSB-BP021799HU CSB-MP021799HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Probable global transcription activator SNF2L2(SMARCA2) ,partial - CSB-EP021799HU from Cusabio Category Protein Species Human

BRM bromodomain (1367-1511 aa) (GST-tagged), Human recombinant - 7655-20 from Biovision Category Protein Prices $175.00 Sizes 20 μg Source E. coli Species Human

BRM bromodomain (1367-1511 aa) (GST-tagged), Human recombinant - 7655-100 from Biovision Category Protein Prices $595.00 Sizes 100 μg Source E. coli Species Human

Probable global transcription activator SNF2L2, Recombinant Protein - MBS953002 from MyBioSource Category Protein Prices $185.00, $420.00, $680.00, $1,070.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Human SMARCA2 Protein, GST-tagged - SMARCA2-193H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SMARCA2 Protein, His-tagged - SMARCA2-194H from Creative Biomart Category Protein Source E.coli Species Human

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