FGB

Gene Symbol	FGB
Entrez Gene	2244
Alt Symbol	HEL-S-78p
Species	Human
Gene Type	protein-coding
Description	fibrinogen beta chain
Other Description	epididymis secretory sperm binding protein Li 78p|fibrinogen, B beta polypeptide
Swissprots	B2R7G3 A0JLR9 Q32Q65 Q3KPF2 P02675
Accessions	AAA18024 AAA98115 AAA98116 AAK62470 CAA28674 CDL78902 EAX04930 EAX04931 EAX04932 EAX04933 EAX04934 EAX04935 EAX04936 EAX04937 EAX04938 EAX04939 P02675 AI174804 AK303788 BAG64745 AK309592 AK311683 AK312972 BAG35810 BC007030 AAH07030 BC036007 BC060040 BC070245 BC106760 AAI06761 BC107766 AAI07767 EU668333 ACF94486 J00129 AAA52429 J00133 T74412 NM_001184741 NP_001171670 NM_005141 NP_005132
Function	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. {ECO:0000250|UniProtKB:E9PV24}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FGB / Fibrinogen Beta Chain ELISA Kit (Sandwich ELISA) - LS-F4481 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 3.4 ng/ml Range 7.81-500 ng/ml

Mouse FGB / Fibrinogen Beta Chain ELISA Kit (Sandwich ELISA) - LS-F5903 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 7.81-500 ng/ml

Rat FGB / Fibrinogen Beta Chain ELISA Kit (Sandwich ELISA) - LS-F8048 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.65 ng/ml Range 7.81-500 ng/ml

Human FGB / Fibrinogen Beta Chain ELISA Kit (Sandwich ELISA) - LS-F11470 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 7.81-500 ng/ml

Fibrinogen Beta, FGb, Human, ELISA Kit - E-EL-H2111 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Fibrinogen Beta (FGb), Human, ELISA Kit - SEB215Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 2.9ng/mL Range 7.8-500ng/mL

Fibrinogen beta chain (FGB), Human, ELISA Kit - E01F0367 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Fibrinogen beta chain, FGB, Human, ELISA Kit - E1307h from ARP American Research Products Category ELISA Kit Prices $636.00 Sizes 96 t Range 0.156-10 nmol/L

Fibrinopeptide B, FPB, Human, ELISA Kit - CSB-E09611h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.2 ng/ml Range 4.7 ng/ml-300 ng/ml

Fibrinogen Beta chain, FGB, Mouse, ELISA Kit - E-EL-M0495 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 2.344 Range 3.906-250ng/mL

Fibrinogen Beta, FGb, Rabbit, ELISA Kit - E-EL-RB2195 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Fibrinogen Beta, FGb, Chicken, ELISA Kit - E-EL-Ch1867 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Fibrinogen Beta, FGb, Porcine, ELISA Kit - E-EL-P1405 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibrinogen Beta, FGb, Sheep, ELISA Kit - E-EL-S0390 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Fibrinogen Beta, FGb, Monkey, ELISA Kit - E-EL-MK0947 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Fibrinogen Beta, ELISA Kit - MBS729088 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS032523 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS043279 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS091158 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS737821 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS011553 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS037924 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS104228 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS031026 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fibrinogen Beta, ELISA Kit - MBS004923 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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