Gene Symbol | UBE2G1 |
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Entrez Gene | 7326 |
Alt Symbol | E217K, UBC7, UBE2G |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2G 1 |
Other Description | ubiquitin carrier protein G1|ubiquitin-conjugating enzyme E2 G1|ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)|ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)|ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7)|ubiquitin-protein ligase G1 |
Swissprots | Q99462 P62253 D3DTK0 B2R7P2 |
Accessions | CAH05704 CAR82353 EAW90441 EAW90442 EAW90443 EAW90444 EAW90445 EAW90446 P62253 AI493944 AK313059 BAG35889 BC002775 AAH02775 BC017006 BC026288 AAH26288 BG703127 BI601205 BT007416 AAP36084 BT008255 AAP36947 BU161770 CD250951 D78514 BAA11410 NM_003342 NP_003333 NM_182682 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. {ECO:0000269|PubMed:19103148, ECO:0000269|PubMed:20061386}. |
Tissue Specificity | Widely expressed, mainly in skeletal muscle. {ECO:0000269|PubMed:8893823}. |
Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
UBE2G1 (G-12) - sc-109118 from Santa Cruz Biotechnology
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UBE2G1 (K-13) - sc-109119 from Santa Cruz Biotechnology
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UBE2G1 (L-12) - sc-109120 from Santa Cruz Biotechnology
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UBE2G1 (G-832) - sc-100619 from Santa Cruz Biotechnology
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UBE2G1 (H-2) - sc-398969 from Santa Cruz Biotechnology
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UBE2G1 (H-50) - sc-367613 from Santa Cruz Biotechnology
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Anti-Ube2G1 antibody - ab172079 from Abcam
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Anti-Ube2G1 antibody - ab58256 from Abcam
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Anti-Ube2G1 antibody - ab101371 from Abcam
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Anti-Ube2G1 antibody - ab116243 from Abcam
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Anti-Ube2G1 antibody - N-terminal - ab135508 from Abcam
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Anti-UBE2G1 Antibody (aa127-155, AP) - LS-C272878 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa127-155, APC) - LS-C272880 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa44-93) - LS-C145206 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa127-155, Biotin) - LS-C272881 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa127-155, FITC) - LS-C272882 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa127-155, Azide-free, HRP) - LS-C272883 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa127-155, PE) - LS-C272884 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, AP) - LS-C283927 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, Biotin) - LS-C283928 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, FITC) - LS-C283929 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, APC) - LS-C283930 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, Azide-free, HRP) - LS-C283931 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (aa126-155) - LS-C326131 from LifeSpan Bioscience
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Anti-UBE2G1 Antibody (N-Terminus, PE) - LS-C283932 from LifeSpan Bioscience
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