Gene Symbol | UBE2G1 |
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Entrez Gene | 7326 |
Alt Symbol | E217K, UBC7, UBE2G |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2G 1 |
Other Description | ubiquitin carrier protein G1|ubiquitin-conjugating enzyme E2 G1|ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)|ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)|ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7)|ubiquitin-protein ligase G1 |
Swissprots | Q99462 P62253 D3DTK0 B2R7P2 |
Accessions | CAH05704 CAR82353 EAW90441 EAW90442 EAW90443 EAW90444 EAW90445 EAW90446 P62253 AI493944 AK313059 BAG35889 BC002775 AAH02775 BC017006 BC026288 AAH26288 BG703127 BI601205 BT007416 AAP36084 BT008255 AAP36947 BU161770 CD250951 D78514 BAA11410 NM_003342 NP_003333 NM_182682 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4. {ECO:0000269|PubMed:19103148, ECO:0000269|PubMed:20061386}. |
Tissue Specificity | Widely expressed, mainly in skeletal muscle. {ECO:0000269|PubMed:8893823}. |
Top Pathways | Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum |
Active human Ube2G1 full length protein - ab188725 from Abcam
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Human Ube2G1 full length protein - ab139614 from Abcam
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Human Ube2G1 full length protein - ab187415 from Abcam
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UBE2G1 Antibody Blocking Peptide - LS-E4786 from LifeSpan Bioscience
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UBE2G1 Antibody Blocking Peptide - LS-E15830 from LifeSpan Bioscience
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UBE2G1 Antibody Blocking Peptide - LS-E6869 from LifeSpan Bioscience
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UBE2G1 Recombinant Protein - H00007326-P01 from Novus Biologicals
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UBE2G1 Peptide - P0898 from Novus Biologicals
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UBE2G1 Peptide - P0897 from Novus Biologicals
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UBE2G1-Antibody-C-term-Blocking-Peptide - BP17162b from Abgent, a WuXi AppTec company
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UBE2G1-Antibody-C-term-Blocking-Peptide - BP2121b from Abgent, a WuXi AppTec company
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UBE2G1-Antibody-N-term-Blocking-Peptide - BP2121a from Abgent, a WuXi AppTec company
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Recombinant Human His6-UBE2G1, CF - E2-700-050 from R&D Systems
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Recombinant Human His6-UBE2G1, CF - E2-700-100 from R&D Systems
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Human UBC7 protein - orb139841 from Biorbyt
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Ubc7 protein - 30R-1045 from Fitzgerald
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UBE2G1 protein (His tag) - 80R-4025 from Fitzgerald
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UBE2G1 (1-170, His-tag) - AR51710PU-N from Acris Antibodies
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UBE2G1 (1-170, His-tag) - AR51710PU-S from Acris Antibodies
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UBE2G1 - SA6047 from Acris Antibodies
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UBE2G1 - SA6047X from Acris Antibodies
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UBE2G1 - H00007326-P01-10 from Acris Antibodies
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UBE2G1 - H00007326-P01-25 from Acris Antibodies
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UBE2G1 fusion protein - Ag2625 from Proteintech Group
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UbC7 Human - GWB-937F85 from Genway Biotech
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