PDIA6

Gene Symbol	PDIA6
Entrez Gene	10130
Alt Symbol	ERP5, P5, TXNDC7
Species	Human
Gene Type	protein-coding
Description	protein disulfide isomerase family A, member 6
Other Description	ER protein 5|endoplasmic reticulum protein 5|protein disulfide isomerase P5|protein disulfide isomerase-associated 6|protein disulfide isomerase-related protein|protein disulfide-isomerase A6|thioredoxin domain containing 7 (protein disulfide isomerase)|thioredoxin domain-containing protein 7
Swissprots	Q6ZSH5 F8WA83 Q15084 B5MCQ5 Q53RC7 Q99778 B3KY95 B7Z254 B7Z4M8
Accessions	AAY24070 EAX00949 EAX00950 Q15084 AK125449 AK127433 BAC86977 AK131234 BAG54757 AK225496 AK289428 BAF82117 AK294347 BAH11740 AK297547 BAH12614 BC001312 AAH01312 BF979486 BM511594 D49489 BAA08450 DA976962 DQ891186 ABM82112 DQ894369 ABM85295 HY166449 U79278 AAB50217 XM_011510308 XP_011508610 NM_001282704 NP_001269633 NM_001282705 NP_001269634 NM_001282706 NP_001269635 NM_001282707 NP_001269636 NM_005742 NP_005733
Function	May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity	Expressed in platelets (at protein level). {ECO:0000269|PubMed:15466936}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PDIA6 full length protein - ab101048 from Abcam Category Protein Source E. coli Species Human

Human PDIA6 full length protein - ab152020 from Abcam Category Protein Source HEK 293 cells Species Human

Human PDIA6 peptide - ab39768 from Abcam Category Peptide Species Human

PDIA6 / ERP5 Antibody Blocking Peptide - LS-E8365 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDIA6 / ERP5 Antibody Blocking Peptide - LS-E8366 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDIA6 / ERP5 Antibody Blocking Peptide - LS-E18706 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDIA6 / ERP5 Antibody Blocking Peptide - LS-E18707 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDIA6 Recombinant Protein - H00010130-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PDIA6 Protein - NBP1-50859 from Novus Biologicals Category Protein Prices $309.00 Sizes 100 µg

PDIA6-Antibody-Center-D251-Blocking-Peptide - BP6662c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDIA6-Antibody-Center-K159-Blocking-Peptide - BP6662b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDIA6 Protein (OPPA02581) - OPPA02581 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human PDIA6 protein - orb169007 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Human PDIA6 protein - orb49609 from Biorbyt Category Protein Prices $323.00, $485.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

PDIA6 Blocking Peptide - 33R-4571 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDIA6 Blocking Peptide - 33R-4499 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDIA6 Blocking Peptide - 33R-4572 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDIA6 protein (His tag) - 80R-1534 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

PDIA6 / P5 (20-440, His-tag) - AR09712PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PDIA6 / P5 (20-440, His-tag) - AR09712PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PDIA6 / P5 - H00010130-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

PDIA6 / P5 Control Peptide - SP5390CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Protein Disulfide Isomerase A6, Human Recombinant - 228-12176-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

PDIA6, 20-440aa, Human, His tag, E.coli - 01-1769-6 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Protein Disulfide Isomerase A6 (PDIA6), Human - 20-8840 from ARP American Research Products Category Protein Prices $457.00 Sizes 50 µg Source E.coli Species Human

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