PDIA6

Gene Symbol PDIA6
Entrez Gene 10130
Alt Symbol ERP5, P5, TXNDC7
Species Human
Gene Type protein-coding
Description protein disulfide isomerase family A, member 6
Other Description ER protein 5|endoplasmic reticulum protein 5|protein disulfide isomerase P5|protein disulfide isomerase-associated 6|protein disulfide isomerase-related protein|protein disulfide-isomerase A6|thioredoxin domain containing 7 (protein disulfide isomerase)|thioredoxin domain-containing protein 7
Swissprots Q6ZSH5 F8WA83 Q15084 B5MCQ5 Q53RC7 Q99778 B3KY95 B7Z254 B7Z4M8
Accessions AAY24070 EAX00949 EAX00950 Q15084 AK125449 AK127433 BAC86977 AK131234 BAG54757 AK225496 AK289428 BAF82117 AK294347 BAH11740 AK297547 BAH12614 BC001312 AAH01312 BF979486 BM511594 D49489 BAA08450 DA976962 DQ891186 ABM82112 DQ894369 ABM85295 HY166449 U79278 AAB50217 XM_011510308 XP_011508610 NM_001282704 NP_001269633 NM_001282705 NP_001269634 NM_001282706 NP_001269635 NM_001282707 NP_001269636 NM_005742 NP_005733
Function May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Expressed in platelets (at protein level). {ECO:0000269|PubMed:15466936}.
Top Pathways Protein processing in endoplasmic reticulum

ERp5 CRISPR/Cas9 KO Plasmid (h) - sc-401739 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 HDR Plasmid (h) - sc-401739-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 Double Nickase Plasmid (h) - sc-401739-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 Double Nickase Plasmid (h2) - sc-401739-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 CRISPR Activation Plasmid (h) - sc-401739-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 CRISPR Activation Plasmid (h2) - sc-401739-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 Lentiviral Activation Particles (h) - sc-401739-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 Lentiviral Activation Particles (h2) - sc-401739-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERp5 siRNA (h) - sc-94493 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERp5 shRNA Plasmid (h) - sc-94493-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERp5 shRNA (h) Lentiviral Particles - sc-94493-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN16563 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16563 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07301 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07301

PDIA6 siRNA (Human) - CRH6832 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PDIA (NM_005742.2) - SHH372768 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PDIA6(NM_005742.2) - SHR102156 from Creative biogene

Category siRNA
Species Reactivities Human

Human PDIA6 siRNA - orb267334 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PDIA6 shRNA Plasmid (Human) - CHH6832 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PDIA6 miRNA 3'UTR clone - MiUTR1H-07742 from Creative biogene

Species Reactivities Human
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