PDIA6

Gene Symbol PDIA6
Entrez Gene 10130
Alt Symbol ERP5, P5, TXNDC7
Species Human
Gene Type protein-coding
Description protein disulfide isomerase family A, member 6
Other Description ER protein 5|endoplasmic reticulum protein 5|protein disulfide isomerase P5|protein disulfide isomerase-associated 6|protein disulfide isomerase-related protein|protein disulfide-isomerase A6|thioredoxin domain containing 7 (protein disulfide isomerase)|thioredoxin domain-containing protein 7
Swissprots Q6ZSH5 F8WA83 Q15084 B5MCQ5 Q53RC7 Q99778 B3KY95 B7Z254 B7Z4M8
Accessions AAY24070 EAX00949 EAX00950 Q15084 AK125449 AK127433 BAC86977 AK131234 BAG54757 AK225496 AK289428 BAF82117 AK294347 BAH11740 AK297547 BAH12614 BC001312 AAH01312 BF979486 BM511594 D49489 BAA08450 DA976962 DQ891186 ABM82112 DQ894369 ABM85295 HY166449 U79278 AAB50217 XM_011510308 XP_011508610 NM_001282704 NP_001269633 NM_001282705 NP_001269634 NM_001282706 NP_001269635 NM_001282707 NP_001269636 NM_005742 NP_005733
Function May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity Expressed in platelets (at protein level). {ECO:0000269|PubMed:15466936}.
Top Pathways Protein processing in endoplasmic reticulum

ERp5 (C-4) - sc-374494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ERp5 (C-4): sc-374494. Western blot analysis of ERp5 expression in K-562 whole cell lysate.

ERp5 (F-5) - sc-376390 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ERp5 (F-5): sc-376390. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ERp5 (G-5) - sc-365260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ERp5 (G-5): sc-365260. Western blot analysis of ERp5 expression in non-transfected 293: sc-110760 (A), human ERp5 transfected 293: sc-110585 (B) and K-562 (C) whole cell lysates.

ERp5 (H-249) - sc-292227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ERp5 (H-249): sc-292227. Immunofluorescence staining of formalin-fixed Hep G2 cells showing cytoplasmic localization.

ERp5 (N-16) - sc-107533 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ERp5 (N-16): sc-107533. Western blot analysis of ERp5 expression in non-transfected 293: sc-110760 (A), human ERp5 transfected 293: sc-110585 (B) and Daudi (C) whole cell lysates.

Anti-PDIA6 antibody - ab11432 from Abcam

Prices $390.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
PDIA6 was immunoprecipitated using 0.5mg Hela whole cell extract, 5µg of Rabbit polyclonal to PDIA6 and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, Hela whole cell extract lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab11432.Secondary: Mouse monoclonal [SB62a] Secondary Antibody to Rabbit IgG light chain (HRP) (ab99697).Band: 48kDa; PDIA6

Anti-PDIA6 antibody - ab37756 from Abcam

Prices $382.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-PDIA6 antibody (ab37756) at 1/2000 dilution + E coli derived fusion protein at 2.5 µgSecondaryGoat anti IgY HRP at 1/1000 dilution

Anti-PDIA6 antibody - ab135594 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PDIA6 antibody (ab135594) at 1/50 dilution + Y79 cell line lysate at 35 µg

Anti-PDIA6 antibody - ab83456 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PDIA6 antibody (ab83456) at 1 µg/ml + 721_B cell lysate at 10 µg with skim milk/ PBS at 5 %SecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PDIA6 antibody [EPR10132(B)] - ab154820 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10132(B)
All lanes : Anti-PDIA6 antibody [EPR10132(B)] (ab154820) at 1/1000 dilutionLane 1 : Human fetal kidney tissue lysateLane 2 : K562 cell lysateLane 3 : HepG2 cell lysateLane 4 : HT 1080 cell lysateLysates/proteins at 10 µg per lane.

Anti-PDIA6 antibody [EPR10132(B)] (Alexa Fluor® 647) - ab201352 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10132(B)
ab201352 staining PDIA6 in HepG2 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab201352 at a 1/50 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at a 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-PDIA6 antibody [EPR10133(B)] - ab154171 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10133(B)
All lanes : Anti-PDIA6 antibody [EPR10133(B)] (ab154171) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : HT-1080 lysateLane 3 : C6 lysateLane 4 : RAW264.7 lysateLane 5 : HepG2 lysateLane 6 : K562 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PDIA6 / ERP5 Antibody (aa144-172) - LS-C163487 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with PDIA6 Antibody (Center K159), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PDIA6 / ERP5 Antibody (aa476-492) - LS-C9546 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PDIA6 / ERP5 Antibody (aa108-157) - LS-C102410 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDIA6 antibody LS-C102410 Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.

Anti-PDIA6 / ERP5 Antibody - LS-C335334 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PDIA6 antibody.

Anti-PDIA6 / ERP5 Antibody - LS-C346205 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of U20S cell using PDIA6 antibody. Blue: DAPI for nuclear staining.

Anti-PDIA6 / ERP5 Antibody (aa236-264) - LS-C97795 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with PDIA6 Antibody (Center D251), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-PDIA6 / ERP5 Antibody (aa216-265) IHC-plus™ - LS-B6893 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PDIA6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6893 concentration 5 ug/ml.

PDIA6 Antibody - NBP1-57999 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PDIA6 Antibody [NBP1-57999] - Sample Type : Mouse Brain lysate

PDIA6 Antibody - NBP1-57968 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PDIA6 Antibody [NBP1-57968] - Human Fetal Lung, Antibody Dilution: 1.0 ug/ml.

PDIA6 Antibody - NBP2-38213 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PDIA6 Antibody [NBP2-38213] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

PDIA6 Antibody - NBP1-84798 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PDIA6 Antibody [NBP1-84798] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11, Lane 2: Human cell line RT-4, Lane 3: Human cell line U-251MG sp

PDIA6 Antibody - NB100-75605 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-PDIA6 )

PDIA6 Antibody - H00010130-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PDIA6 Antibody [H00010130-B01P] - Analysis of PDIA6 expression in human liver.
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