TCF7L1

Gene Symbol	TCF7L1
Entrez Gene	83439
Alt Symbol	TCF-3, TCF3
Species	Human
Gene Type	protein-coding
Description	transcription factor 7-like 1 (T-cell specific, HMG-box)
Other Description	HMG box transcription factor 3|transcription factor 7-like 1
Swissprots	Q9NP00 Q53R97 Q6PD70 Q9HCS4
Accessions	AAY15068 AAY24094 CAB91064 EAW99542 Q9HCS4 AB031046 BAB18185 BC058894 AAH58894 BF434361 XM_006712109 XP_006712172 NM_031283 NP_112573
Function	Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. {ECO:0000250}.
Subcellular Location	Nucleus.
Tissue Specificity	Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. {ECO:0000269|PubMed:9916915}.
Top Pathways	Hippo signaling pathway, Wnt signaling pathway, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Thyroid cancer, Prostate cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TCF7L1 protein fragment - ab164388 from Abcam Category Protein Source Wheat germ Species Human

TCF3 / E2A Antibody Blocking Peptide - LS-E2868 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TCF3 / E2A Antibody Blocking Peptide - LS-E10819 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TCF3 / E2A Antibody Blocking Peptide - LS-E30866 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TCF3 / E2A Antibody Blocking Peptide - LS-E13744 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TCF3 / E2A Antibody Blocking Peptide - LS-E26246 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TCF7L1 / TCF-3 Antibody Blocking Peptide - LS-E10477 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TCF7L1 / TCF-3 Antibody Blocking Peptide - LS-E21173 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TCF-3/E2A Protein - H00006929-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TCF7L1/TCF3 Protein - H00083439-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TCF-3/E2A Peptide - NBP1-77119PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

TCF3 Blocking Peptide - 33R-10627 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TCF3 Blocking Peptide - abx063331 from Abbexa Category Peptide Species Human, Chicken

TCF7L1 - H00083439-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TCF7L1 - H00083439-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TCF7L1 fusion protein - ag5983 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Transcription factor 7-like 1(TCF7L1) - CSB-YP884626HU CSB-EP884626HU CSB-BP884626HU CSB-MP884626HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TCF3/E2A, Peptide - MBS843935 from MyBioSource Category Peptide Prices $165.00 Sizes 50 µg

TCF-3/E2A Recombinant Protein Antigen - NBP2-38611PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TCF-3/E2A Protein - NBP2-38961PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TCF7L1-Blocking-Peptide-N-term - BP20423a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TCF3 Peptide, Human - M34GP15726H from Creative Peptides Category Peptide Source Synthetic. Species Human

TCF3 Immunizing peptide - orb17309 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

TCF7L1/TCF3 Recombinant Protein Antigen - NBP2-56055PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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