NLRP4

Gene Symbol	NLRP4
Entrez Gene	147945
Alt Symbol	CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2
Species	Human
Gene Type	protein-coding
Description	NLR family, pyrin domain containing 4
Other Description	NACHT, LRR and PYD containing protein 4|NACHT, LRR and PYD domains-containing protein 4|NACHT, leucine rich repeat and PYD containing 4|PAAD and NACHT-containing protein 2|PYRIN and NACHT-containing protein 2|PYRIN-containing APAF1-like protein 4|cancer/testis antigen 58|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4|ribonuclease inhibitor 2
Swissprots	Q96AY6 Q86W87 Q96MN2
Accessions	EAW72417 EAW72418 Q96MN2 AF442488 AAL35293 AF479747 AAL87104 AF482706 AAL88672 AK056688 BAB71254 AK315003 BAG37498 AY072792 AAL68396 BC012789 BC016443 AAH16443 BC021272 BC050326 AAH50326 BE302040 BU632773 XM_006723042 XP_006723105 XM_006723043 XP_006723106 XM_011526515 XP_011524817 XM_011526516 XP_011524818 NM_134444 NP_604393
Function	May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways. {ECO:0000269|PubMed:12093792, ECO:0000269|PubMed:22388039}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NALP4 / NLRP4 Antibody Blocking Peptide - LS-E6120 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NALP4 / NLRP4 Antibody Blocking Peptide - LS-E30990 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PAN2 / USP52 Antibody Blocking Peptide - LS-E4363 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human USP52 Protein - H00009924-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NALP4 Blocking Peptide - NBP1-76288PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

NLRP4-Antibody-N-term-Blocking-Peptide - BP18739a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WISP2 Recombinant Protein (Active) - GTX48100-PRO from GeneTex Category Protein Prices $299.00 Sizes 20 μg Source E. coli Species Human

NALP4 control peptide - AP26261CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NALP4 Peptide - 5957P from ProSci Category Peptide Species Human

Recombinant Human NACHT, LRR and PYD domains-containing protein 4(NLRP4) ,partial - CSB-YP839375HU CSB-EP839375HU CSB-BP839375HU CSB-MP839375HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NALP4 Recombinant Protein Antigen - NBP1-85554PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NLRP4 Peptide, Human - M34GP10440H from Creative Peptides Category Peptide Source Synthetic. Species Human

PAN2 Peptide, Human - M34GP11274H from Creative Peptides Category Peptide Source Synthetic. Species Human

NACHT, LRR and PYD domains-containing protein 4 (NLRP4), partial, Recombinant Protein - MBS1325103 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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