PTGES3

Gene Symbol	PTGES3
Entrez Gene	10728
Alt Symbol	P23, TEBP, cPGES
Species	Human
Gene Type	protein-coding
Description	prostaglandin E synthase 3 (cytosolic)
Other Description	Hsp90 co-chaperone|cytosolic prostaglandin E synthase|cytosolic prostaglandin E2 synthase|progesterone receptor complex p23|prostaglandin E synthase 3|telomerase-binding protein p23|unactive progesterone receptor, 23 kD
Swissprots	Q8WU70 B4DHP2 A8K7D0 B4DP21 Q15185 B4DP11
Accessions	EAW96953 EAW96954 EAW96955 EAW96956 EAW96957 EAW96958 Q15185 AK098214 BAG53594 AK291945 BAF84634 AK293139 BAG56687 AK295208 BAG58204 AK298147 BAG60423 AK298160 BAG60433 AL603017 BC003005 AAH03005 BC021167 AAH21167 BG927063 BM541503 BP194632 BU167210 BU732883 CA773263 DA556848 DQ896710 ABM87709 EU176396 ABW03847 L24804 AAA18537 Z69891 XM_005268576 XP_005268633 XM_006719199 XP_006719262 XM_011537773 XP_011536075 XM_011537774 XP_011536076 NM_001282601 NP_001269530 NM_001282602 NP_001269531 NM_001282603 NP_001269532 NM_001282604 NP_001269533 NM_001282605 NP_001269534 NM_006601 NP_006592 NR_104219
Function	Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448). {ECO:0000269|PubMed:10922363, ECO:0000269|PubMed:11274138, ECO:0000269|PubMed:12077419, ECO:0000269|PubMed:24711448}.
Subcellular Location	Cytoplasm.
Top Pathways	Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat PTGES3 / p23 ELISA Kit (Cell-Based ELISA) - LS-F2345 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-PTGES3 / p23 (Ser113) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1228 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Human PTGES3 / p23 ELISA Kit (Sandwich ELISA) - LS-F12708 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Prostaglandin E synthase 3, PTGES3, Human, ELISA Kit - E10319h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

TEBP Colorimetric Cell-Based ELISA Kit - CB5677 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TEBP (Phospho-Ser113) Colorimetric Cell-Based ELISA Kit - CBP1222 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

prostaglandin E synthase 3 (cytosolic) , ELISA Kit - MBS921770 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human PTGES3 is typically less than 7.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml-2000 pg/ml.

Prostaglandin F, ELISA Kit - MBS024833 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS018443 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS039699 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS042528 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS016936 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS057648 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS041026 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS031063 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS091738 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS042587 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS026231 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS021881 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS023177 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS031392 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F - MBS023970 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

Prostaglandin F, ELISA Kit - MBS077485 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS092855 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin F, ELISA Kit - MBS068319 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more