MGEA5

Gene Symbol MGEA5
Entrez Gene 10724
Alt Symbol MEA5, NCOAT, OGA
Species Human
Gene Type protein-coding
Description meningioma expressed antigen 5 (hyaluronidase)
Other Description N-acetyl-beta-D-glucosaminidase|N-acetyl-beta-glucosaminidase|O-GlcNAcase|beta-N-acetylglucosaminidase|beta-N-acetylhexosaminidase|beta-hexosaminidase|bifunctional protein NCOAT|hyaluronidase in meningioma|meningioma-expressed antigen 5|nuclear cytoplasmic O-GlcNAcase and acetyltransferase|protein O-GlcNAcase
Swissprots Q9HAR0 O60502 Q86WV0 Q9BVA5 E9PGF9 O75166 B7WPB9 D3DR79 Q8IV98
Accessions EAW49741 EAW49742 EAW49743 EAW49744 O60502 AB014579 BAA31654 AF036144 AAD05385 AF307332 AAG21428 AK000988 AK002091 BAG51014 AK027008 AK302626 BAG63869 BC001343 AAH01343 BC014201 BC032591 BC039583 AAH39583 BC047877 AAH47877 BQ016159 DC353958 XM_011539180 XP_011537482 XM_011539181 XP_011537483 XM_011539182 XP_011537484 XR_246060 XR_945587 XR_945588 NM_001142434 NP_001135906 NM_012215 NP_036347
Function Isoform 1: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714). {ECO:0000269|PubMed:11148210, ECO:0000269|PubMed:11788610, ECO:0000269|PubMed:20673219, ECO:0000269|PubMed:22365600, ECO:0000269|PubMed:24088714}.
Subcellular Location Isoform 3: Nucleus {ECO:0000269|PubMed:11341771}.
Tissue Specificity Ubiquitous. Shows highest expression in the brain, placenta and pancreas. {ECO:0000269|PubMed:11148210, ECO:0000269|PubMed:11341771}.

NCOAT CRISPR/Cas9 KO Plasmid (h) - sc-402329 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT HDR Plasmid (h) - sc-402329-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT Double Nickase Plasmid (h) - sc-402329-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT Double Nickase Plasmid (h2) - sc-402329-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT CRISPR Activation Plasmid (h) - sc-402329-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT CRISPR Activation Plasmid (h2) - sc-402329-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT Lentiviral Activation Particles (h) - sc-402329-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT Lentiviral Activation Particles (h2) - sc-402329-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCOAT siRNA (h) - sc-62667 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCOAT shRNA Plasmid (h) - sc-62667-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCOAT shRNA (h) Lentiviral Particles - sc-62667-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU073541 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13301 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13301 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10838 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10838

MGEA5 siRNA (Human) - CRH7306 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

O-GlcNAcase/OGA/MGEA5 RNAi - H00010724-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MGEA5 (NM_012215.3) - SHH341655 from Creative biogene

Category siRNA
Species Reactivities Human

Human MGEA5 siRNA - orb267808 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MGEA5 shRNA Plasmid (Human) - CHH7306 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MGEA5 miRNA 3'UTR clone - MiUTR4H-TG05509 from Creative biogene

Species Reactivities Human
Search more