Gene Symbol | ZMPSTE24 |
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Entrez Gene | 10269 |
Alt Symbol | FACE-1, FACE1, HGPS, PRO1, STE24, Ste24p |
Species | Human |
Gene Type | protein-coding |
Description | zinc metallopeptidase STE24 |
Other Description | CAAX prenyl protease 1 homolog|farnesylated proteins-converting enzyme 1|prenyl protein-specific endoprotease 1|zinc metallopeptidase STE24 homolog|zinc metalloproteinase Ste24 homolog |
Swissprots | Q9UBQ2 D3DPU7 O75844 B3KQI7 Q8NDZ8 |
Accessions | CAF85955 CAF86212 EAX07233 EAX07234 O75844 AA436253 AB016068 BAA33727 AF064867 AAC68866 AI003768 AK027874 BAG51388 AK074784 AK075007 BAG52049 BC037283 AAH37283 DA398037 DB096663 DB285015 EU176257 ABW03708 EU176564 ABW03365 Y13834 CAB46277 XM_011540486 XP_011538788 XM_011540487 XP_011538789 NM_005857 NP_005848 |
Function | Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:23539603}; Multi-pass membrane protein {ECO:0000269|PubMed:23539603}. Nucleus inner membrane {ECO:0000269|PubMed:23539603}; Multi-pass membrane protein {ECO:0000269|PubMed:23539603}. |
Tissue Specificity | Widely expressed. High levels in kidney, prostate, testis and ovary. |
Top Pathways | Terpenoid backbone biosynthesis |
FACE-1 (C-13) - sc-34777 from Santa Cruz Biotechnology
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FACE-1 (D-16) - sc-34778 from Santa Cruz Biotechnology
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FACE-1 (H-170) - sc-66886 from Santa Cruz Biotechnology
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FACE-1 (U-24) - sc-130755 from Santa Cruz Biotechnology
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Anti-ZMPSTE24 antibody - ab38450 from Abcam
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Anti-ZMPSTE24 antibody - Carboxyterminal end - ab70952 from Abcam
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Anti-ZMPSTE24 antibody - Carboxyterminal end - ab53533 from Abcam
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Anti-ZMPSTE24 Antibody (aa400-475) - LS-C49013 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, Biotin) - LS-C141018 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa1-100) - LS-C49012 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, DY650) - LS-C141019 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa83-132) - LS-C80915 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa464-475) - LS-C54807 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, HRP) - LS-C141021 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, DY550) - LS-C141022 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, DY488) - LS-C141020 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa404-433, AP) - LS-C274065 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa404-433, APC) - LS-C274066 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (Internal, APC) - LS-C274069 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa404-433, PE) - LS-C274068 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (aa404-433, FITC) - LS-C274067 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (Internal, AP) - LS-C274071 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (Internal, PE) - LS-C274072 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (Internal, FITC) - LS-C274070 from LifeSpan Bioscience
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Anti-ZMPSTE24 Antibody (C-Terminus, AP) - LS-C284391 from LifeSpan Bioscience
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