Gene Symbol | ZMPSTE24 |
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Entrez Gene | 10269 |
Alt Symbol | FACE-1, FACE1, HGPS, PRO1, STE24, Ste24p |
Species | Human |
Gene Type | protein-coding |
Description | zinc metallopeptidase STE24 |
Other Description | CAAX prenyl protease 1 homolog|farnesylated proteins-converting enzyme 1|prenyl protein-specific endoprotease 1|zinc metallopeptidase STE24 homolog|zinc metalloproteinase Ste24 homolog |
Swissprots | Q9UBQ2 D3DPU7 O75844 B3KQI7 Q8NDZ8 |
Accessions | CAF85955 CAF86212 EAX07233 EAX07234 O75844 AA436253 AB016068 BAA33727 AF064867 AAC68866 AI003768 AK027874 BAG51388 AK074784 AK075007 BAG52049 BC037283 AAH37283 DA398037 DB096663 DB285015 EU176257 ABW03708 EU176564 ABW03365 Y13834 CAB46277 XM_011540486 XP_011538788 XM_011540487 XP_011538789 NM_005857 NP_005848 |
Function | Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:23539603}; Multi-pass membrane protein {ECO:0000269|PubMed:23539603}. Nucleus inner membrane {ECO:0000269|PubMed:23539603}; Multi-pass membrane protein {ECO:0000269|PubMed:23539603}. |
Tissue Specificity | Widely expressed. High levels in kidney, prostate, testis and ovary. |
Top Pathways | Terpenoid backbone biosynthesis |
Human ZMPSTE24 full length protein - ab160917 from Abcam
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Human ZMPSTE24 protein fragment - ab160918 from Abcam
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ZMPSTE24 Antibody Blocking Peptide - LS-E16983 from LifeSpan Bioscience
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ZMPSTE24 Antibody Blocking Peptide - LS-E26172 from LifeSpan Bioscience
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ZMPSTE24 Antibody Blocking Peptide - LS-E6957 from LifeSpan Bioscience
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ZMPSTE24 Antibody Blocking Peptide - LS-E6958 from LifeSpan Bioscience
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ZMPSTE24 Blocking Peptide - NB100-2388PEP from Novus Biologicals
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ZMPSTE24 Blocking Peptide - NB100-2387PEP from Novus Biologicals
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ZMPSTE24 Partial Recombinant Protein - H00010269-Q01 from Novus Biologicals
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ZMPSTE24 Recombinant Protein - H00010269-P01 from Novus Biologicals
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ZMPSTE24 Peptide - P1095 from Novus Biologicals
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ZMPSTE24 Peptide - P1094 from Novus Biologicals
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ZMPSTE24-Antibody-C-term-Blocking-Peptide - BP2415b from Abgent, a WuXi AppTec company
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ZMPSTE24-Antibody-Center-Blocking-Peptide - BP2415a from Abgent, a WuXi AppTec company
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ZMPSTE24 blocking peptide - GTX89219-PEP from GeneTex
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ZMPSTE24 Blocking Peptide - 33R-5572 from Fitzgerald
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ZMPSTE24 Peptide - AC21-1002-P from Abcore
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ZMPSTE24 - H00010269-P01-10 from Acris Antibodies
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ZMPSTE24 - H00010269-P01-25 from Acris Antibodies
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ZMPSTE24 - H00010269-Q01-10 from Acris Antibodies
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ZMPSTE24 - H00010269-Q01-25 from Acris Antibodies
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FACE1 Peptide - 45-562P from ProSci
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ZMPSTE24 fusion protein - ag3949 from Proteintech Group
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CAAX prenyl protease 1 homolog (ZMPSTE24), Recombinant Protein - MBS1205244 from MyBioSource
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FACE1/ZMPSTE24, Peptide - MBS426490 from MyBioSource
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