Gene Symbol | WDR82 |
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Entrez Gene | 80335 |
Alt Symbol | MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 82 |
Other Description | WD repeat-containing protein 82|transmembrane protein 113 |
Swissprots | Q8TEB2 A8K5R5 Q6UXN9 |
Accessions | EAW65202 EAW65203 Q6UXN9 AF132207 AAG35553 AF173977 AAQ13620 AI478905 AK074290 BAB85039 AK098435 AK123860 AK130177 AK291380 BAF84069 AY358264 AAQ88631 BC011760 AAH11760 BC018941 AAH18941 BX648628 DB500464 XM_011534136 XP_011532438 XM_011534137 XP_011532439 NM_025222 NP_079498 |
Function | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. {ECO:0000269|PubMed:17998332, ECO:0000269|PubMed:18838538, ECO:0000269|PubMed:20516061}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16253997, ECO:0000269|PubMed:17355966, ECO:0000269|PubMed:20516061}. Note=Associates with chromatin. |
Top Pathways | mRNA surveillance pathway |
WDR82 (K-14) - sc-103325 from Santa Cruz Biotechnology
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Anti-WDR82 antibody - N-terminal - ab202398 from Abcam
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Anti-WDR82 / TMEM113 Antibody (aa2-31, AP) - LS-C218444 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31, APC) - LS-C218445 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31, Biotin) - LS-C218446 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31, FITC) - LS-C218447 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31, Azide-free, HRP) - LS-C218448 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31, PE) - LS-C218450 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa2-31) - LS-C330295 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa1-30) - LS-C160606 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa12-46) - LS-C344543 from LifeSpan Bioscience
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Anti-WDR82 / TMEM113 Antibody (aa50-85) - LS-C344540 from LifeSpan Bioscience
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ANTI-WDR82 (N-TERM) antibody produced in rabbit - SAB1301144 from Sigma-Aldrich
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WDR82 Antibody - N-terminal region (ARP75796_P050) - ARP75796_P050 from Aviva Systems Biology
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WDR82 Antibody - N-terminal region (OAAB02229) - OAAB02229 from Aviva Systems Biology
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WDR82-Antibody-N-term - AP4812a from Abgent, a WuXi AppTec company
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WDR82-Antibody-N-term - AP20977b from Abgent, a WuXi AppTec company
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WDR82-Antibody-N-term - AP20978b from Abgent, a WuXi AppTec company
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WDR82-Antibody-N-term - AW5310 from Abgent, a WuXi AppTec company
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WDR82 antibody - orb35107 from Biorbyt
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WDR82 Antibody - abx032316 from Abbexa
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Rabbit Anti-Human WDR82 (N-term) - 102-15768 from RayBiotech
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WDR82 antibody (N-term) - STJ49241 from St John's Laboratory Ltd
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Anti-WDR82 monoclonal antibody - DCABH-201721 from Creative Diagnostics
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Anti-WDR82 (aa 2-31) polyclonal antibody - DPABH-11422 from Creative Diagnostics
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