Gene Symbol | WDR82 |
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Entrez Gene | 80335 |
Alt Symbol | MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 82 |
Other Description | WD repeat-containing protein 82|transmembrane protein 113 |
Swissprots | Q8TEB2 A8K5R5 Q6UXN9 |
Accessions | EAW65202 EAW65203 Q6UXN9 AF132207 AAG35553 AF173977 AAQ13620 AI478905 AK074290 BAB85039 AK098435 AK123860 AK130177 AK291380 BAF84069 AY358264 AAQ88631 BC011760 AAH11760 BC018941 AAH18941 BX648628 DB500464 XM_011534136 XP_011532438 XM_011534137 XP_011532439 NM_025222 NP_079498 |
Function | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. {ECO:0000269|PubMed:17998332, ECO:0000269|PubMed:18838538, ECO:0000269|PubMed:20516061}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16253997, ECO:0000269|PubMed:17355966, ECO:0000269|PubMed:20516061}. Note=Associates with chromatin. |
Top Pathways | mRNA surveillance pathway |
Human WDR82 full length protein - ab164261 from Abcam
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WDR82 / TMEM113 Antibody Blocking Peptide - LS-E7604 from LifeSpan Bioscience
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Recombinant Human WDR82 Protein - H00080335-P01 from Novus Biologicals
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WDR82-Antibody-N-term-Blocking-Peptide - BP4812a from Abgent, a WuXi AppTec company
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TMEM113 / WDR82 - H00080335-P01 from Acris Antibodies
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WDR82 fusion protein - ag15578 from Proteintech Group
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WDR82 fusion protein - Ag15762 from Proteintech Group
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Recombinant Human WD repeat-containing protein 82(WDR82) - CSB-YP747639HU CSB-EP747639HU CSB-BP747639HU CSB-MP747639HU from Cusabio
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WD repeat-containing protein 82 (WDR82) , Recombinant Protein - MBS1355930 from MyBioSource
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WDR82-Blocking-Peptide-N-term - BP20977b from Abgent, a WuXi AppTec company
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WDR82 Peptide, Human - M34GP17458H from Creative Peptides
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WDR82 Recombinant Protein Antigen - NBP2-57428PEP from Novus Biologicals
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Recombinant Human WDR82 Protein, His-tagged - WDR82-21H from Creative Biomart
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