Gene Symbol | MSRB1 |
---|---|
Entrez Gene | 51734 |
Alt Symbol | HSPC270, SELR, SELX, SEPX1, SepR |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase B1 |
Other Description | methionine-R-sulfoxide reductase B1|selenoprotein R|selenoprotein X, 1 |
Swissprots | Q9NZV6 Q9BTV2 Q9P0B1 Q96RX6 |
Accessions | AAK61300 EAW85600 EAW85601 Q9NZV6 AF161388 AAF28948 AF166124 AAF21429 AF187272 AAG17033 AK026128 BC003127 AAH03127 CF134919 NM_016332 NP_057416 |
Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post- translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)- sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. |
Selenoprotein R (E-14) - sc-34846 from Santa Cruz Biotechnology
|
||||||||||
Selenoprotein R (H-94) - sc-67072 from Santa Cruz Biotechnology
|
||||||||||
Selenoprotein R (P-14) - sc-34848 from Santa Cruz Biotechnology
|
||||||||||
Selenoprotein R (QA-V7) - sc-135558 from Santa Cruz Biotechnology
|
||||||||||
Anti-Methionine Sulfoxide Reductase B antibody - ab71175 from Abcam
|
||||||||||
Anti-SEPX1 / Selenoprotein R Antibody (aa1-116, FITC) - LS-C302748 from LifeSpan Bioscience
|
||||||||||
Anti-SEPX1 / Selenoprotein R Antibody (aa1-116, Biotin) - LS-C297347 from LifeSpan Bioscience
|
||||||||||
Anti-SEPX1 / Selenoprotein R Antibody (aa1-116) - LS-C296368 from LifeSpan Bioscience
|
||||||||||
Anti-SEPX1 / Selenoprotein R Antibody - LS-C334912 from LifeSpan Bioscience
|
||||||||||
Anti-SEPX1 / Selenoprotein R Antibody (clone 8B2) - LS-C134074 from LifeSpan Bioscience
|
||||||||||
Methionine Sulfoxide Reductase B Antibody (8B2) - H00051734-M02 from Novus Biologicals
|
||||||||||
Methionine Sulfoxide Reductase B Antibody - H00051734-B01 from Novus Biologicals
|
||||||||||
Methionine Sulfoxide Reductase B Antibody - H00051734-D01P from Novus Biologicals
|
||||||||||
Methionine Sulfoxide Reductase B Antibody - H00051734-A01 from Novus Biologicals
|
||||||||||
Monoclonal Anti-SEPX1 antibody produced in mouse - WH0051734M2 from Sigma-Aldrich
|
||||||||||
Anti-SEPX1 antibody produced in rabbit - SAB1410949 from Sigma-Aldrich
|
||||||||||
SEPX1-Antibody-monoclonal-M02 - AT3815a from Abgent, a WuXi AppTec company
|
||||||||||
MSRB1 Polyclonal Antibody - A6737 from ABclonal
|
||||||||||
Methionine sulfoxide reductase B antibody - 20R-2931 from Fitzgerald
|
||||||||||
MSRB1 Antibody - abx005168 from Abbexa
|
||||||||||
SEPX1 / MSRB1 antibody - 15333-1-AP from Acris Antibodies
|
||||||||||
SEPX1 / MSRB1 antibody - H00051734-A01 from Acris Antibodies
|
||||||||||
SEPX1 / MSRB1 antibody - H00051734-B01 from Acris Antibodies
|
||||||||||
SEPX1 / MSRB1 antibody - H00051734-D01P from Acris Antibodies
|
||||||||||
SEPX1 / MSRB1 antibody - H00051734-M02 from Acris Antibodies
|