Gene Symbol | MSRB1 |
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Entrez Gene | 51734 |
Alt Symbol | HSPC270, SELR, SELX, SEPX1, SepR |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase B1 |
Other Description | methionine-R-sulfoxide reductase B1|selenoprotein R|selenoprotein X, 1 |
Swissprots | Q9NZV6 Q9BTV2 Q9P0B1 Q96RX6 |
Accessions | AAK61300 EAW85600 EAW85601 Q9NZV6 AF161388 AAF28948 AF166124 AAF21429 AF187272 AAG17033 AK026128 BC003127 AAH03127 CF134919 NM_016332 NP_057416 |
Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post- translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)- sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. |
Human Methionine Sulfoxide Reductase B (mutated ) full length protein - ab82652 from Abcam
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Human Methionine Sulfoxide Reductase B full length protein - ab99522 from Abcam
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Methionine Sulfoxide Reductase B Recombinant Protein - H00051734-P01 from Novus Biologicals
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Methionine Sulfoxide Reductase B Partial Recombinant Protein - H00051734-Q01 from Novus Biologicals
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Recombinant Human Methionine Sulfoxide Reductase B Protein - NBP1-49302 from Novus Biologicals
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Recombinant Bacterial Methionine Sulfoxide Reductase B Protein - NBP1-72288 from Novus Biologicals
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Methionine Sulfoxide Reductase B Recombinant Protein - P4999 from Novus Biologicals
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SEPX1-Antibody-Center-Blocking-Peptide - BP16904c from Abgent, a WuXi AppTec company
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SEPX1 Protein (OPPA02505) - OPPA02505 from Aviva Systems Biology
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Human SEPX1 protein - orb169275 from Biorbyt
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Methionine Sulfoxide Reductase B protein - 30R-2995 from Fitzgerald
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SEPX1 protein (His tag) - 80R-1497 from Fitzgerald
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Human Selenoprotein X1 Protein - abx069018 from Abbexa
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SEPX1 / MSRB1 (1-116, His-tag) - AR09673PU-L from Acris Antibodies
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SEPX1 / MSRB1 (1-116, His-tag) - AR09673PU-N from Acris Antibodies
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SEPX1 / MSRB1 - H00051734-P01-10 from Acris Antibodies
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SEPX1 / MSRB1 - H00051734-P01-25 from Acris Antibodies
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SEPX1 / MSRB1 - H00051734-Q01-10 from Acris Antibodies
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SEPX1 / MSRB1 - H00051734-Q01-25 from Acris Antibodies
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Selenoprotein X1 (SEPX1), Human - 20-8966 from ARP American Research Products
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SEPX1, 1-116aa, Human, His tag, E.coli - 01-SEPX-1 from ARP American Research Products
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SEPX1 fusion protein - ag7975 from Proteintech Group
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SEPX1 fusion protein - Ag7391 from Proteintech Group
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SEPX1 Human - PRPS-267 from NeoScientific
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Recombinant Human SEPX1 Protein - BP002278-PRO-260 from Syd Labs
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