PPP1R16B

Gene Symbol PPP1R16B
Entrez Gene 26051
Alt Symbol ANKRD4, TIMAP
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 16B
Other Description CAAX box protein TIMAP|TGF-beta-inhibited membrane-associated protein|ankyrin repeat domain protein 4|ankyrin repeat domain-containing protein 4|hTIMAP|protein phosphatase 1 regulatory inhibitor subunit 16B|protein phosphatase 1, regulatory (inhibitor) subunit 16B
Swissprots Q9NQG4 Q96T49 Q5W9G4 O94912 E9PFS8 A2RRR6
Accessions EAW76009 Q96T49 AB020630 BAA74846 AB177855 BAD66833 AF362910 AAK52796 AK026900 AK311244 BC026224 BC131801 AAI31802 BC152467 AAI52468 XM_011528768 XP_011527070 XM_011528769 XP_011527071 NM_001172735 NP_001166206 NM_015568 NP_056383
Function Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells. {ECO:0000269|PubMed:16263087, ECO:0000269|PubMed:18586956}.
Subcellular Location Cell membrane. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Nucleus. Note=Colocalizes with RPSA/LAMR1 in the cell membrane.
Tissue Specificity Highly expressed in vascular endothelium, CNS, lung, spleen, kidney and testis.

TIMAP (G-20) - sc-79618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

TIMAP (W-17) - sc-79620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B antibody - ab92851 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PPP1R16B antibody (ab92851) at 1/500 dilutionLane 1 : Extracts from mouse brain cellsLane 2 : Extracts from mouse brain cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-PPP1R16B antibody - ab67892 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PPP1R16B antibody (ab67892) at 1/500 dilutionLane 1 : PPP1R16B transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PPP1R16B antibody [EPR10293(B)] - ab154834 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10293(B)
All lanes : Anti-PPP1R16B antibody [EPR10293(B)] (ab154834) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PPP1R16B Antibody (aa372-399, AP) - LS-C223738 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa372-399, Biotin) - LS-C223739 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa372-399, APC) - LS-C223740 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa372-399, Azide-free, HRP) - LS-C223742 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa372-399, FITC) - LS-C223741 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa372-399, PE) - LS-C223743 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa371-399) - LS-C324232 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP1R16B Antibody (aa57-106) - LS-C146221 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPP1R16B antibody LS-C146221 Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.

Anti-PPP1R16B Antibody (aa364-413) - LS-C120259 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from mouse brain cells, using PPP1R16B Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PPP1R16B Antibody (Internal) - LS-C345700 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PP16B Antibody with human 721_B Whole Cell lysate.

Anti-PPP1R16B Antibody (aa372-399) - LS-C158712 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PPP1R16B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The PPP1R16B antibody detected the PPP1R16B protein (arrow).

PPP1R16B Antibody - NBP2-13799 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PPP1R16B Antibody [NBP2-13799] Staining of human kidney shows strong membranous and cytoplasmic positivity in cells in glomeruli while renal tubules showed moderate cytoplasmic staining.

PPP1R16B Antibody - H00026051-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PPP1R16B Antibody [H00026051-D01P] - Analysis of PPP1R16B expression in transfected 293T cell line by PPP1R16B polyclonal antibody.Lane 1: PPP1R16B transfected lysate(63.60 KDa).Lane 2: Non-transfected lysate.

PPP1R16B Antibody - H00026051-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PPP1R16B Antibody [H00026051-B01P] - Analysis of PPP1R16B expression in transfected 293T cell line by PPP1R16B polyclonal antibody. Lane 1: PPP1R16B transfected lysate(62.37 KDa). Lane 2: Non-transfected lysate.

Anti-PPP1R16B antibody produced in rabbit - SAB1401619 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PPP1R16B, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401619</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~63.60 kDa using PPP1R16B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PPP1R16B antibody produced in mouse - SAB1407278 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPP1R16B: <B>Cat. No. SAB1407278</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~62.4 kDa using PPP1R16B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PPP1R16B antibody produced in rabbit - HPA049571 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPP1R16B:<B>Cat. No. HPA049571</B>: Immunohistochemical staining of human kidney shows strong membranous and cytoplasmic positivity in cells in glomeruli while renal tubules showed moderate cytoplasmic staining.

Anti-PPP1R16B antibody produced in rabbit - SAB4501110 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPP1R16B: <B>Cat. No. SAB4501110</B>: Immunoblotting analysis of extracts from mouse brain cells, using Anti-PPP1R16B antibody. The lane on the left was treated with the Anti-PPP1R16B antibody. The lane on the right (negative control) was treated with both Anti-PPP1R16B antibody and the synthesized immunogen peptide.

PPP1R16B antibody - N-terminal region (ARP62226_P050) - ARP62226_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PP16B Antibody - middle region (ARP74139_P050) - ARP74139_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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