PPP1R16B

Gene Symbol	PPP1R16B
Entrez Gene	26051
Alt Symbol	ANKRD4, TIMAP
Species	Human
Gene Type	protein-coding
Description	protein phosphatase 1, regulatory subunit 16B
Other Description	CAAX box protein TIMAP|TGF-beta-inhibited membrane-associated protein|ankyrin repeat domain protein 4|ankyrin repeat domain-containing protein 4|hTIMAP|protein phosphatase 1 regulatory inhibitor subunit 16B|protein phosphatase 1, regulatory (inhibitor) subunit 16B
Swissprots	Q9NQG4 Q96T49 Q5W9G4 O94912 E9PFS8 A2RRR6
Accessions	EAW76009 Q96T49 AB020630 BAA74846 AB177855 BAD66833 AF362910 AAK52796 AK026900 AK311244 BC026224 BC131801 AAI31802 BC152467 AAI52468 XM_011528768 XP_011527070 XM_011528769 XP_011527071 NM_001172735 NP_001166206 NM_015568 NP_056383
Function	Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells. {ECO:0000269|PubMed:16263087, ECO:0000269|PubMed:18586956}.
Subcellular Location	Cell membrane. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Nucleus. Note=Colocalizes with RPSA/LAMR1 in the cell membrane.
Tissue Specificity	Highly expressed in vascular endothelium, CNS, lung, spleen, kidney and testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PPP1R16B full length protein - ab161884 from Abcam Category Protein Source Wheat germ Species Human

PPP1R16B Antibody Blocking Peptide - LS-E5160 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP1R16B Antibody Blocking Peptide - LS-E22734 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPP1R16B Recombinant Protein - H00026051-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PPP1R16B-Antibody-Center-Blocking-Peptide - BP17590c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPP1R16B - H00026051-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PPP1R16B - H00026051-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PPP1R16B fusion protein - ag18990 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PPP1R16B fusion protein - Ag19269 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human PPP1R16B, GST-tagged - PPP1R16B-1906H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B(PPP1R16B) - CSB-YP842762HU CSB-EP842762HU CSB-BP842762HU CSB-MP842762HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PPP1R16B - TP318476 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PPP1R16B Protein - NBP2-13799PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PPP1R16B Peptide, Human - M34GP12243H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B), Recombinant Protein - MBS1413823 from MyBioSource Category Protein Prices $1,360.00, $1,360.00, $1,580.00, $1,580.00, $2,260.00, $2,260.00, $2,725.00, $2,725.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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