PPP1R16B

Gene Symbol PPP1R16B
Entrez Gene 26051
Alt Symbol ANKRD4, TIMAP
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 16B
Other Description CAAX box protein TIMAP|TGF-beta-inhibited membrane-associated protein|ankyrin repeat domain protein 4|ankyrin repeat domain-containing protein 4|hTIMAP|protein phosphatase 1 regulatory inhibitor subunit 16B|protein phosphatase 1, regulatory (inhibitor) subunit 16B
Swissprots Q9NQG4 Q96T49 Q5W9G4 O94912 E9PFS8 A2RRR6
Accessions EAW76009 Q96T49 AB020630 BAA74846 AB177855 BAD66833 AF362910 AAK52796 AK026900 AK311244 BC026224 BC131801 AAI31802 BC152467 AAI52468 XM_011528768 XP_011527070 XM_011528769 XP_011527071 NM_001172735 NP_001166206 NM_015568 NP_056383
Function Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells. {ECO:0000269|PubMed:16263087, ECO:0000269|PubMed:18586956}.
Subcellular Location Cell membrane. Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Nucleus. Note=Colocalizes with RPSA/LAMR1 in the cell membrane.
Tissue Specificity Highly expressed in vascular endothelium, CNS, lung, spleen, kidney and testis.

TIMAP CRISPR/Cas9 KO Plasmid (h) - sc-417353 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP HDR Plasmid (h) - sc-417353-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP Double Nickase Plasmid (h) - sc-417353-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP Double Nickase Plasmid (h2) - sc-417353-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP CRISPR Activation Plasmid (h) - sc-417353-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP CRISPR Activation Plasmid (h2) - sc-417353-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP Lentiviral Activation Particles (h) - sc-417353-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP Lentiviral Activation Particles (h2) - sc-417353-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIMAP siRNA (h) - sc-76669 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIMAP shRNA Plasmid (h) - sc-76669-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIMAP shRNA (h) Lentiviral Particles - sc-76669-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU154631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0564 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0563 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0562 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17271 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17271 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPP1R16B siRNA (Human) - CRH8681 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PPP1R16B (NM_015568.2) - SHH381148 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPP1R16B siRNA - orb269183 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPP1R16B shRNA Plasmid (Human) - CHH8681 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPP1R16B miRNA 3'UTR clone - MiUTR1H-08181 from Creative biogene

Species Reactivities Human
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