Gene Symbol | GPN1 |
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Entrez Gene | 11321 |
Alt Symbol | ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1 |
Species | Human |
Gene Type | protein-coding |
Description | GPN-loop GTPase 1 |
Other Description | ATP(GTP)-binding protein|MBD2-interacting protein|RNA polymerase II associated protein 4|RNAPII-associated protein 4|XPA binding protein 1, GTPase |
Swissprots | B4DXU4 B4DQJ5 O76004 B4DQM4 B5MBZ5 Q9HCN4 |
Accessions | AAX93201 EAX00557 EAX00558 Q9HCN4 AB044661 BAB17612 AJ010842 CAA09376 AK298827 BAG60957 AK298866 BAG60986 AK302131 BAG63506 AK310340 AK311423 AK312992 BAG35829 AK316404 BAH14775 BC007451 AAH07451 DQ893280 ABM84206 DQ896611 ABM87610 NM_001145047 NP_001138519 NM_001145048 NP_001138520 NM_001145049 NP_001138521 NM_007266 NP_009197 NR_026735 |
Function | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544, ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11058119, ECO:0000269|PubMed:20855544}. Nucleus {ECO:0000269|PubMed:20855544}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20855544}. |
Tissue Specificity | Expressed ubiquitously. |
GPN1 - MBS1266625 from MyBioSource
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Human GPN1 cDNA clone(NM_001145048.1) - CDFH007849 from Creative Biomart
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Human GPN1 cDNA clone(NM_001145047.1) - CDFH007850 from Creative Biomart
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Human GPN1 cDNA clone(NM_001145049.1) - CDFH007851 from Creative Biomart
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Human GPN1 cDNA clone(NM_007266.3) - CDFH007853 from Creative Biomart
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Human GPN1 ORF Clone(NM_007266.3) - CDCR294750 from Creative Biomart
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Human GPN1 ORF Clone(NM_007266.3) - CDCR294753 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145047.1) - CDCR352398 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145048.1) - CDCR352399 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145048.1) - CDCR352400 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145049.1) - CDCR352441 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145047.1) - CDCR352442 from Creative Biomart
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Human GPN1 ORF Clone(NM_001145049.1) - CDCR352443 from Creative Biomart
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Human GPN1 ORF clone (NM_001145047.1) - CDCL113725 from Creative biogene
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Mouse GPN1 ORF clone (NM_001145048.1) - CDCL113727 from Creative biogene
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Human GPN1 ORF clone (NM_001145049.1) - CDCL113729 from Creative biogene
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Mouse GPN1 ORF clone (NM_007266.3) - CDCL113731 from Creative biogene
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Human GPN1 ORF Clone (BC007451) - CDCS408446 from Creative biogene
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Human GPN1 cDNA Clone(NM_001145048.1) - CDFH007849 from Creative biogene
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Human GPN1 cDNA Clone(NM_001145047.1) - CDFH007850 from Creative biogene
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Human GPN1 cDNA Clone(NM_001145049.1) - CDFH007851 from Creative biogene
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Human GPN1 cDNA Clone(NM_007266.3) - CDFH007853 from Creative biogene
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