GPN1

Gene Symbol GPN1
Entrez Gene 11321
Alt Symbol ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1
Species Human
Gene Type protein-coding
Description GPN-loop GTPase 1
Other Description ATP(GTP)-binding protein|MBD2-interacting protein|RNA polymerase II associated protein 4|RNAPII-associated protein 4|XPA binding protein 1, GTPase
Swissprots B4DXU4 B4DQJ5 O76004 B4DQM4 B5MBZ5 Q9HCN4
Accessions AAX93201 EAX00557 EAX00558 Q9HCN4 AB044661 BAB17612 AJ010842 CAA09376 AK298827 BAG60957 AK298866 BAG60986 AK302131 BAG63506 AK310340 AK311423 AK312992 BAG35829 AK316404 BAH14775 BC007451 AAH07451 DQ893280 ABM84206 DQ896611 ABM87610 NM_001145047 NP_001138519 NM_001145048 NP_001138520 NM_001145049 NP_001138521 NM_007266 NP_009197 NR_026735
Function Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544, ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11058119, ECO:0000269|PubMed:20855544}. Nucleus {ECO:0000269|PubMed:20855544}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20855544}.
Tissue Specificity Expressed ubiquitously.

Human XAB1 full length protein - ab128455 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of 3 µg ab128455.

GPN1 / XAB1 Antibody Blocking Peptide - LS-E4355 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

XAB1 Partial Recombinant Protein - H00011321-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

XAB1 Recombinant Protein - H00011321-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human XAB1 Protein - NBP1-98928 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human

GPN1-Antibody-C-term-Blocking-Peptide - BP16654b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human GPN1 protein - orb168425 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 25 μg
Species Human

XAB1 protein (His tag) - 80R-2341 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

GPN1 / XAB1 - H00011321-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

GPN1 / XAB1 - H00011321-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

GPN1 / XAB1 - H00011321-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

GPN1 / XAB1 - H00011321-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

XAB1 (1-374, His-tag) - AR50425PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
XAB1

XAB1 (1-374, His-tag) - AR50425PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
XAB1

XAB1, 1-374aa, Human, His tag, E.coli - 01-P1601 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

GPN1 fusion protein - Ag8252 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

GPN1 Human - PRPS-1147 from NeoScientific

Category Protein
Prices $65.00, $169.00, $3,510.00
Sizes 5 µg, 25 µg, 1 mg
Source E.coli.
Species Human

Recombinant human GPN1 Protein - BP002854-PRO-1140 from Syd Labs

Category Protein
Prices $160.00, $2,700.00
Sizes 25 µg, 1 mg
Source E. coli-derived.
Species Human

XAB1, 1-374aa, Recombinant Protein - GWB-P0437H from Genway Biotech

Category Protein
Prices $300.00, $900.00
Sizes 100 μg, 500 μg
Source E.coli
Species Human

Recombinant Human GPN-Loop GTPase 1, His-tagged - GPN1-6847H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human GPN1, GST-tagged - GPN1-13429H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human GPN-loop GTPase 1(GPN1) - CSB-YP009724HU CSB-EP009724HU CSB-BP009724HU CSB-MP009724HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

GPN1 / XAB1 (transcript variant 1) - TP301406 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
GPN1 / XAB1

XAB1, Recombinant Protein - MBS204271 from MyBioSource

Category Protein
Prices $310.00, $720.00
Sizes 100 µg, 500 µg
Source E Coli
Species Human

XAB1 Recombinant Protein Antigen - NBP2-38332PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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