Gene Symbol | GPN1 |
---|---|
Entrez Gene | 11321 |
Alt Symbol | ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1 |
Species | Human |
Gene Type | protein-coding |
Description | GPN-loop GTPase 1 |
Other Description | ATP(GTP)-binding protein|MBD2-interacting protein|RNA polymerase II associated protein 4|RNAPII-associated protein 4|XPA binding protein 1, GTPase |
Swissprots | B4DXU4 B4DQJ5 O76004 B4DQM4 B5MBZ5 Q9HCN4 |
Accessions | AAX93201 EAX00557 EAX00558 Q9HCN4 AB044661 BAB17612 AJ010842 CAA09376 AK298827 BAG60957 AK298866 BAG60986 AK302131 BAG63506 AK310340 AK311423 AK312992 BAG35829 AK316404 BAH14775 BC007451 AAH07451 DQ893280 ABM84206 DQ896611 ABM87610 NM_001145047 NP_001138519 NM_001145048 NP_001138520 NM_001145049 NP_001138521 NM_007266 NP_009197 NR_026735 |
Function | Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544, ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11058119, ECO:0000269|PubMed:20855544}. Nucleus {ECO:0000269|PubMed:20855544}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20855544}. |
Tissue Specificity | Expressed ubiquitously. |
Human XAB1 full length protein - ab128455 from Abcam
|
||||||||||
GPN1 / XAB1 Antibody Blocking Peptide - LS-E4355 from LifeSpan Bioscience
|
||||||||||
XAB1 Partial Recombinant Protein - H00011321-Q01 from Novus Biologicals
|
||||||||||
XAB1 Recombinant Protein - H00011321-P01 from Novus Biologicals
|
||||||||||
Recombinant Human XAB1 Protein - NBP1-98928 from Novus Biologicals
|
||||||||||
GPN1-Antibody-C-term-Blocking-Peptide - BP16654b from Abgent, a WuXi AppTec company
|
||||||||||
Human GPN1 protein - orb168425 from Biorbyt
|
||||||||||
XAB1 protein (His tag) - 80R-2341 from Fitzgerald
|
||||||||||
GPN1 / XAB1 - H00011321-P01-10 from Acris Antibodies
|
||||||||||
GPN1 / XAB1 - H00011321-P01-25 from Acris Antibodies
|
||||||||||
GPN1 / XAB1 - H00011321-Q01-10 from Acris Antibodies
|
||||||||||
GPN1 / XAB1 - H00011321-Q01-25 from Acris Antibodies
|
||||||||||
XAB1 (1-374, His-tag) - AR50425PU-N from Acris Antibodies
|
||||||||||
XAB1 (1-374, His-tag) - AR50425PU-S from Acris Antibodies
|
||||||||||
XAB1, 1-374aa, Human, His tag, E.coli - 01-P1601 from ARP American Research Products
|
||||||||||
GPN1 fusion protein - Ag8252 from Proteintech Group
|
||||||||||
GPN1 Human - PRPS-1147 from NeoScientific
|
||||||||||
Recombinant human GPN1 Protein - BP002854-PRO-1140 from Syd Labs
|
||||||||||
XAB1, 1-374aa, Recombinant Protein - GWB-P0437H from Genway Biotech
|
||||||||||
Recombinant Human GPN-Loop GTPase 1, His-tagged - GPN1-6847H from Creative Biomart
|
||||||||||
Recombinant Human GPN1, GST-tagged - GPN1-13429H from Creative Biomart
|
||||||||||
Recombinant Human GPN-loop GTPase 1(GPN1) - CSB-YP009724HU CSB-EP009724HU CSB-BP009724HU CSB-MP009724HU from Cusabio
|
||||||||||
GPN1 / XAB1 (transcript variant 1) - TP301406 from Acris Antibodies
|
||||||||||
XAB1, Recombinant Protein - MBS204271 from MyBioSource
|
||||||||||
XAB1 Recombinant Protein Antigen - NBP2-38332PEP from Novus Biologicals
|