GPN1

Gene Symbol GPN1
Entrez Gene 11321
Alt Symbol ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1
Species Human
Gene Type protein-coding
Description GPN-loop GTPase 1
Other Description ATP(GTP)-binding protein|MBD2-interacting protein|RNA polymerase II associated protein 4|RNAPII-associated protein 4|XPA binding protein 1, GTPase
Swissprots B4DXU4 B4DQJ5 O76004 B4DQM4 B5MBZ5 Q9HCN4
Accessions AAX93201 EAX00557 EAX00558 Q9HCN4 AB044661 BAB17612 AJ010842 CAA09376 AK298827 BAG60957 AK298866 BAG60986 AK302131 BAG63506 AK310340 AK311423 AK312992 BAG35829 AK316404 BAH14775 BC007451 AAH07451 DQ893280 ABM84206 DQ896611 ABM87610 NM_001145047 NP_001138519 NM_001145048 NP_001138520 NM_001145049 NP_001138521 NM_007266 NP_009197 NR_026735
Function Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544, ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11058119, ECO:0000269|PubMed:20855544}. Nucleus {ECO:0000269|PubMed:20855544}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20855544}.
Tissue Specificity Expressed ubiquitously.

GPN1 CRISPR/Cas9 KO Plasmid (h) - sc-411602 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 HDR Plasmid (h) - sc-411602-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 Double Nickase Plasmid (h) - sc-411602-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 Double Nickase Plasmid (h2) - sc-411602-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 CRISPR Activation Plasmid (h) - sc-411602-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 CRISPR Activation Plasmid (h2) - sc-411602-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 Lentiviral Activation Particles (h) - sc-411602-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPN1 Lentiviral Activation Particles (h2) - sc-411602-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XAB1 siRNA (h) - sc-94614 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XAB1 shRNA Plasmid (h) - sc-94614-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XAB1 shRNA (h) Lentiviral Particles - sc-94614-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XAB1 RNAi - H00011321-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU002491 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9534 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9534 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06045 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06045

GPN1 siRNA (Human) - CRH7751 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPN1 - MBS8210563 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPN1 (NM_007266.3) - SHH305974 from Creative biogene

Category siRNA
Species Reactivities Human

Human GPN1 siRNA - orb268253 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPN1 shRNA Plasmid (Human) - CHH7751 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPN1 miRNA 3'UTR clone - MiUTR3H-11922 from Creative biogene

Species Reactivities Human

GPN1 miRNA 3'UTR clone - MiUTR3H-11923 from Creative biogene

Species Reactivities Human

GPN1 miRNA 3'UTR clone - MiUTR3H-11924 from Creative biogene

Species Reactivities Human

GPN1 miRNA 3'UTR clone - MiUTR3H-11925 from Creative biogene

Species Reactivities Human
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