MAML2

Gene Symbol	MAML2
Entrez Gene	84441
Alt Symbol	MAM-3, MAM2, MAM3, MLL-MAML2
Species	Human
Gene Type	protein-coding
Description	mastermind-like 2 (Drosophila)
Other Description	mam-2|mastermind-like protein 2
Swissprots	Q8IZL2 Q96JK6 Q6AI23 A7MD26
Accessions	EAW66975 Q8IZL2 AB058722 BAB47448 AK308157 AW513171 AY040322 AAK93831 BC143529 AAI43530 BC152449 AAI52450 CR627398 CAH10491 DA862475 XM_011543023 XP_011541325 XM_011543024 XP_011541326 XM_011543025 XP_011541327 NM_032427 NP_115803
Function	Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3. {ECO:0000269|PubMed:12370315, ECO:0000269|PubMed:12386158, ECO:0000269|PubMed:12539049}.
Subcellular Location	Nucleus speckle {ECO:0000269|PubMed:12370315}. Note=Nuclear, in a punctate manner.
Tissue Specificity	Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle. {ECO:0000269|PubMed:14720503}.
Top Pathways	Notch signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAML2 peptide - ab68318 from Abcam Category Peptide

Human MAML2 protein fragment - ab164591 from Abcam Category Protein Source Wheat germ Species Human

MAML2 Antibody Blocking Peptide - LS-E13505 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAML2 Antibody Blocking Peptide - LS-E13506 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MAML2 Protein - H00084441-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Mastermind-like protein 2 - H00084441-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Mastermind-like protein 2 - H00084441-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAML2 fusion protein - ag20412 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MAML2 fusion protein - ag20163 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MAML2, GST-tagged - MAML2-718H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Mastermind-like protein 2(MAML2) ,partial - CSB-YP809028HU CSB-EP809028HU CSB-BP809028HU CSB-MP809028HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MAML2 Recombinant Protein Antigen - NBP1-82891PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAML2-Blocking-Peptide-Center - BP21469c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAML2 Peptide, Human - M34GP09128H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mastermind-like protein 2 (MAML2), partial, Recombinant Protein - MBS1349921 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more