MAML2

Gene Symbol MAML2
Entrez Gene 84441
Alt Symbol MAM-3, MAM2, MAM3, MLL-MAML2
Species Human
Gene Type protein-coding
Description mastermind-like 2 (Drosophila)
Other Description mam-2|mastermind-like protein 2
Swissprots Q8IZL2 Q96JK6 Q6AI23 A7MD26
Accessions EAW66975 Q8IZL2 AB058722 BAB47448 AK308157 AW513171 AY040322 AAK93831 BC143529 AAI43530 BC152449 AAI52450 CR627398 CAH10491 DA862475 XM_011543023 XP_011541325 XM_011543024 XP_011541326 XM_011543025 XP_011541327 NM_032427 NP_115803
Function Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3. {ECO:0000269|PubMed:12370315, ECO:0000269|PubMed:12386158, ECO:0000269|PubMed:12539049}.
Subcellular Location Nucleus speckle {ECO:0000269|PubMed:12370315}. Note=Nuclear, in a punctate manner.
Tissue Specificity Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle. {ECO:0000269|PubMed:14720503}.
Top Pathways Notch signaling pathway

MAML2 CRISPR/Cas9 KO Plasmid (h) - sc-409346 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 HDR Plasmid (h) - sc-409346-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 Double Nickase Plasmid (h) - sc-409346-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 Double Nickase Plasmid (h2) - sc-409346-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 CRISPR Activation Plasmid (h) - sc-409346-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 CRISPR Activation Plasmid (h2) - sc-409346-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 Lentiviral Activation Particles (h) - sc-409346-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 Lentiviral Activation Particles (h2) - sc-409346-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MAML2 siRNA (h) - sc-75742 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAML2 shRNA Plasmid (h) - sc-75742-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAML2 shRNA (h) Lentiviral Particles - sc-75742-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAML2 RNAi - H00084441-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU011931 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12957 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12957 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05800 from Sigma-Aldrich

Category miRNA

MAML2 siRNA (Human) - CRJ3474 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAML2 (NM_032427.1) - SHH337199 from Creative biogene

Category siRNA
Species Reactivities Human

Human MAML2 siRNA - orb273975 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MAML2 shRNA Plasmid (Human) - CHJ3474 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAML2 miRNA 3'UTR clone - MiUTR1H-06031 from Creative biogene

Species Reactivities Human
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