Gene Symbol | SNRPC |
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Entrez Gene | 6631 |
Alt Symbol | U1C, Yhc1 |
Species | Human |
Gene Type | protein-coding |
Description | small nuclear ribonucleoprotein polypeptide C |
Other Description | U1 small nuclear RNP specific C|U1 small nuclear ribonucleoprotein C|U1 snRNP C|U1 snRNP protein C|U1-C|U1C |
Swissprots | P09234 Q5TAL3 |
Accessions | CAJ42725 EAX03795 EAX03796 EAX03797 P09234 AI356808 AK223098 BAD96818 AK311955 BAG34895 BC121082 AAI21083 BC121083 AAI21084 BU153661 BU508721 CD109745 M18465 AAA36618 X12517 CAA31037 NM_003093 NP_003084 NR_029472 |
Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. {ECO:0000269|PubMed:1826349, ECO:0000269|PubMed:2136774, ECO:0000269|PubMed:8798632}. |
Subcellular Location | Nucleus. |
Top Pathways | Spliceosome |
Human SNRPC full length protein - ab117010 from Abcam
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Human SNRPC full length protein - ab116159 from Abcam
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SNRPC-Antibody-C-term-Blocking-Peptide - BP2841b from Abgent, a WuXi AppTec company
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SNRPC protein (His tag) - 80R-2065 from Fitzgerald
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snRNP-C / SNRPC (1-159, His-tag) - AR50148PU-N from Acris Antibodies
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snRNP-C / SNRPC (1-159, His-tag) - AR50148PU-S from Acris Antibodies
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snRNP-C / SNRPC - H00006631-P01-10 from Acris Antibodies
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snRNP-C / SNRPC - H00006631-P01-25 from Acris Antibodies
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snRNP-C / SNRPC - P299-3 from Acris Antibodies
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Small Nuclear Ribonucleoprotein Polypeptide C, Human Recombinant - 228-12824-1 from RayBiotech
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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide C - 228-12824-2 from RayBiotech
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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide C - 228-12824-3 from RayBiotech
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SNRPC, 1-159aa, Human, His tag, E.coli - 01-P1323 from ARP American Research Products
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SNRPC fusion protein - ag18190 from Proteintech Group
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Recombinant Human SNRPC protein - BP002063-PRO-1004 from Syd Labs
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SNRPC, 1-159aa, Recombinant Protein - GWB-P0715M from Genway Biotech
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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide C, His-tagged - SNRPC-1323H from Creative Biomart
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Recombinant Human SNRPC - SNRPC-30583TH from Creative Biomart
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Recombinant Human SNRPC, His-tagged - SNRPC-30605TH from Creative Biomart
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SNRPC 1-159aa - CMB-1156 from Reagent Proteins
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Recombinant Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) - RPB374Hu01 from Uscn Life Science Inc.
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Recombinant Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC) - RPB374Hu01 from Cloud-clone
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Recombinant U1 small nuclear ribonucleoprotein C(TP01_1168) - CSB-YP708960TCK CSB-EP708960TCK CSB-BP708960TCK CSB-MP708960TCK from Cusabio
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Recombinant U1 small nuclear ribonucleoprotein C(TA09515) - CSB-YP700204TCJ CSB-EP700204TCJ CSB-BP700204TCJ CSB-MP700204TCJ from Cusabio
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Recombinant U1 small nuclear ribonucleoprotein C (CBG19656) - CSB-YP022331CXX CSB-EP022331CXX CSB-BP022331CXX CSB-MP022331CXX from Cusabio
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