SNRPC

Gene Symbol SNRPC
Entrez Gene 6631
Alt Symbol U1C, Yhc1
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptide C
Other Description U1 small nuclear RNP specific C|U1 small nuclear ribonucleoprotein C|U1 snRNP C|U1 snRNP protein C|U1-C|U1C
Swissprots P09234 Q5TAL3
Accessions CAJ42725 EAX03795 EAX03796 EAX03797 P09234 AI356808 AK223098 BAD96818 AK311955 BAG34895 BC121082 AAI21083 BC121083 AAI21084 BU153661 BU508721 CD109745 M18465 AAA36618 X12517 CAA31037 NM_003093 NP_003084 NR_029472
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. {ECO:0000269|PubMed:1826349, ECO:0000269|PubMed:2136774, ECO:0000269|PubMed:8798632}.
Subcellular Location Nucleus.
Top Pathways Spliceosome

SNRPC CRISPR/Cas9 KO Plasmid (h) - sc-404002 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC HDR Plasmid (h) - sc-404002-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC Double Nickase Plasmid (h) - sc-404002-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC Double Nickase Plasmid (h2) - sc-404002-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC CRISPR Activation Plasmid (h) - sc-404002-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC CRISPR Activation Plasmid (h2) - sc-404002-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC Lentiviral Activation Particles (h) - sc-404002-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC Lentiviral Activation Particles (h2) - sc-404002-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC siRNA (h) - sc-95371 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNRPC shRNA Plasmid (h) - sc-95371-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNRPC shRNA (h) Lentiviral Particles - sc-95371-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU106451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20269 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20269 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00492 from Sigma-Aldrich

Category miRNA

SNRPC siRNA (Human) - CRH4513 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNRPC - MBS8206529 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNRPC CRISPR/Cas9 KO Plasmid (h2) - sc-404002-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC HDR Plasmid (h2) - sc-404002-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNRPC shRNA Plasmid (Human) - CHH4513 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNRPC miRNA 3'UTR clone - MiUTR3H-06050 from Creative biogene

Species Reactivities Human
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