SNRPC

Gene Symbol SNRPC
Entrez Gene 6631
Alt Symbol U1C, Yhc1
Species Human
Gene Type protein-coding
Description small nuclear ribonucleoprotein polypeptide C
Other Description U1 small nuclear RNP specific C|U1 small nuclear ribonucleoprotein C|U1 snRNP C|U1 snRNP protein C|U1-C|U1C
Swissprots P09234 Q5TAL3
Accessions CAJ42725 EAX03795 EAX03796 EAX03797 P09234 AI356808 AK223098 BAD96818 AK311955 BAG34895 BC121082 AAI21083 BC121083 AAI21084 BU153661 BU508721 CD109745 M18465 AAA36618 X12517 CAA31037 NM_003093 NP_003084 NR_029472
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. {ECO:0000269|PubMed:1826349, ECO:0000269|PubMed:2136774, ECO:0000269|PubMed:8798632}.
Subcellular Location Nucleus.
Top Pathways Spliceosome

SNRPC (C-2) - sc-374428 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNRPC (C-2): sc-374428. Western blot analysis of SNRPC expression in HeLa (A) and K-562 (B) nuclear extracts.

SNRPC (E-10) - sc-376552 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNRPC (E-10): sc-376552. Western blot analysis of SNRPC expression in HeLa (A) and K-562 (B) nuclear extracts.

SNRPC (E-14) - sc-169379 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNRPC (E-14): sc-169379. Western blot analysis of SNRPC expression in mouse liver tissue extract (A) and c4 whole cell lysate (B).

SNRPC (5C9) - sc-101548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
SNRPC (5C9): sc-101548. Western blot analysis of SNRPC expression in K-562 (A), Jurkat (B) and HeLa (C) nuclear extracts and Hep G2 (D) and OV-90 (E) whole cell lysates.

SNRPC (H-70) - sc-292035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SNRPC (H-70): sc-292035. Western blot analysis of SNRPC expression in non-transfected: sc-117752 (A) and mouse SNRPC transfected: sc-123687 (B) 293T whole cell lysates.

SNRPC (4H12) - sc-101549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
SNRPC (4H12): sc-101549. Western blot analysis of SNRPC expression in K-562 (A), HeLa (B) and Jurkat (C) nuclear extracts and ES-2 (D) and c4 (E) whole cell lysates.

Anti-SNRPC [EPR16034] antibody - ab192028 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16034
All lanes : Anti-SNRPC [EPR16034] antibody (ab192028) at 1/5000 dilutionLane 1 : Jurkat cell lysateLane 2 : K562 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-SNRPC antibody [4H12] - ab122901 from Abcam

Prices $384.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 4H12
ab122901 staining SNRPC in Mouse L929 cells by Immunoflourescence (green). Right image shows the cells DNA stained with Hoechst.

Anti-SNRPC antibody - C-terminal - ab82862 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SNRPC antibody - C-terminal (ab82862) at 1/50 dilution + K562 cell line lysates at 35 µg

Anti-SNRPC / U1C Antibody (aa2-159) - LS-C314768 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SNRPC / U1C.

Anti-SNRPC / U1C Antibody (aa133-159) - LS-C97332 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with SNRPC Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-SNRPC / U1C Antibody (aa109-159) - LS-C290590 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human U1C by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-U1C antibody used for IP at 6 ug/mg lysate. For blotting immunoprecipitated U1C, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

SNRPC Antibody - NBP2-38755 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPC Antibody [NBP2-38755] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG

SNRPC Antibody - NBP2-22299 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNRPC Antibody [NBP2-22299] - Whole cell lysate (50 ug) from Renca and TCMK-1 cells.  NBP2-22299 used for WB at 1 ug/ml.  Detection: Chemiluminescence with an exposure time of 3 minutes.

Monoclonal Anti-U1 snRNP C (U1C) antibody produced in rat - SAB4200188 from Sigma-Aldrich

Prices $55.60, $360.00
Sizes 25 µl, 200 µl
Host Rat
Clonality Monoclonal
Clone 4H12
<B>Immunoblotting</B><BR/>Cell lysates were separated on SDS-PAGE and probed with 1 μg/mL Rat Anti-U1 snRNP C Clone: 4H12 (<B>Cat. No. SAB4200188</B>). The antibody was developed using Rabbit Anti-RAT IgG-Peroxidase (<B>Cat. No. A9542</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. CHO<BR/>2. 3T3<BR/>3. COS-7<BR/>4. HeLa

Anti-SNRPC (C-term) antibody produced in rabbit - SAB1300710 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPC (C-term) Antibody: <B>Cat. No. SAB1300710</B>: SNRPC in K562 cell line lysates with Anti-SNRPC (C-term) Antibody at 4.0 μg/mL.

ANTI-SNRPC(C-TERMINAL) antibody produced in rabbit - SAB1307173 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SNRPC (C-term): <B>Cat. No. SAB1307173</B>: Western blot analysis of Anti-SNRPC (C-term) in K562 cell line lysates (35 μg/lane).

SNRPC Antibody - C-terminal region (OAAB01572) - OAAB01572 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SNRPC-Antibody-C-term - AP2841b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-SNRPC Antibody (C-term) (Cat.#AP2841b) in K562 cell line lysates (35ug/lane). SNRPC(arrow) was detected using the purified Pab.

snRNP-C / SNRPC (C-term) antibody - AP12499PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of anti-SNRPC Antibody (C-term) (Cat.#AP12499PU-N) in K562 cell line lysates (35ug/lane). SNRPC(arrow) was detected using the purified Pab.

Rabbit Anti-Human SNRPC (C-term) - 102-15178 from RayBiotech

Host Rabbit
Western blot analysis of anti-SNRPC Antibody (C-term) (Cat# 102-15178) in K562 cell line lysates (35ug/lane). SNRPC(arrow) was detected using the purified Pab.

SNRPC antibody (C-term) - STJ48636 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB17340

SNRPC, Polyclonal Antibody - MBS630773 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNRPC (aa 109-159) polyclonal antibody - DPABH-05777 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

U1C Antibody - A303-947A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal
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