ZFYVE16

Gene Symbol	ZFYVE16
Entrez Gene	9765
Alt Symbol	PPP1R69
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 16
Other Description	endosome-associated FYVE-domain protein\|protein phosphatase 1, regulatory subunit 69\|zinc finger FYVE domain-containing protein 16
Swissprots	Q8NEK3 Q7LAU7 Q7Z3T8 Q8N5L3 O15023 Q86T69 Q5H9U2
Accessions	EAW95850 EAW95851 Q7Z3T8 AB002303 BAA20764 AF434817 AAL30772 AK090896 AK127003 BAG54419 AL833087 CAD89968 AW952550 BC030808 AAH30808 BC032227 BX537424 CAD97666 BX649172 BX956000 CB854699 CR933621 CAI45932 DA216169 DB208042 DR005686 XM_005248632 XP_005248689 XM_005248634 XP_005248691 XM_011543752 XP_011542054 XM_011543753 XP_011542055 XM_011543754 XP_011542056 XM_011543755 XP_011542057 XM_011543756 XP_011542058 NM_001105251 NP_001098721 NM_001284236 NP_001271165 NM_001284237 NP_001271166 NM_014733 NP_055548
Function	May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. {ECO:0000269\|PubMed:11546807, ECO:0000269\|PubMed:14613930}.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:11546807}. Early endosome membrane {ECO:0000269\|PubMed:11546807}; Peripheral membrane protein {ECO:0000269\|PubMed:11546807}. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
Tissue Specificity	Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. {ECO:0000269\|PubMed:11546807}.
Top Pathways	TGF-beta signaling pathway, Endocytosis

ZFYVE16 (1H6) - sc-135608 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

ZFYVE16 (1H6): sc-135608. Western blot analysis of ZFYVE16 expression in human ZFYVE16 transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-ZFYVE16 antibody - ab103683 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 antibody (ab103683) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-ZFYVE16 antibody - ab56771 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Western blot against tagged recombinant protein immunogen using ab56771 ZFYVE16 antibody at 1ug/ml.

Anti-ZFYVE16 Antibody (aa375-404, AP) - LS-C274025 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404, APC) - LS-C274026 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404, Biotin) - LS-C274027 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404, FITC) - LS-C274028 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404, PE) - LS-C274030 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404, Azide-free, HRP) - LS-C274029 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa380-410) - LS-C326497 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa369-623) - LS-C178986 from LifeSpan Bioscience

Prices	$255.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ZFYVE16 Antibody (aa375-404) - LS-C160786 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

ZFYVE16 Antibody IHC of formalin-fixed and paraffin-embedded lung tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

ZFYVE16 Antibody - NBP1-81516 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: ZFYVE16 Antibody [NBP1-81516] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & vesicles.

ZFYVE16 Antibody - NBP1-81517 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: ZFYVE16 Antibody [NBP1-81517] - Staining of human cell line U-251 MG shows localization to cytosol & vesicles.

ZFYVE16 Antibody (4B9) - H00009765-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4B9

Western Blot: ZFYVE16 Antibody (4B9) [H00009765-M01] - Analysis of ZFYVE16 expression in transfected 293T cell line by ZFYVE16 monoclonal antibody (M01), clone 4B9.Lane 1: ZFYVE16 transfected lysate(88.4 KDa).Lane 2: Non-transfected lysate.

ZFYVE16 Antibody - NBP2-36539 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ZFYVE16 Antibody - NBP2-36538 from Novus Biologicals

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: ZFYVE16 Antibody [NBP2-36538] - Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Endofin antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.

ZFYVE16 Antibody (2E2) - H00009765-M04 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2E2

Western Blot: ZFYVE16 Antibody (2E2) [H00009765-M04] - Analysis of ZFYVE16 expression in HepG2 (Cat # L019V1).

ZFYVE16 Antibody - H00009765-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

ZFYVE16 Antibody - H00009765-D01 from Novus Biologicals

Prices	$399.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Monoclonal Anti-ZFYVE16 antibody produced in mouse - WH0009765M1 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4B9

<B>Immunoblotting</B><BR/>Monoclonal Anti-ZFYVE16, <B>Cat. No. WH0009765M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

Anti-ZFYVE16 antibody produced in rabbit - HPA035936 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-ZFYVE16: <B>Cat. No. HPA035936</B>: Immunohistochemical staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.

Anti-ZFYVE16 antibody produced in mouse - SAB1406876 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-ZFYVE16: <B>Cat. No. SAB1406876</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~89 kDa using ZFYVE16 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ZFYVE16 antibody produced in rabbit - HPA035935 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-ZFYVE16: <B>Cat. No. HPA035935</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Monoclonal Anti-ZFYVE16, (N-terminal) antibody produced in mouse - SAB1404756 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2E2

<B>Immunoblotting</B><BR/>Monoclonal Anti-ZFYVE16: <B>Cat. No. SAB1404756</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~168.8 kDa using HepG2 lysate.

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