ZFYVE16

Gene Symbol ZFYVE16
Entrez Gene 9765
Alt Symbol PPP1R69
Species Human
Gene Type protein-coding
Description zinc finger, FYVE domain containing 16
Other Description endosome-associated FYVE-domain protein|protein phosphatase 1, regulatory subunit 69|zinc finger FYVE domain-containing protein 16
Swissprots Q8NEK3 Q7LAU7 Q7Z3T8 Q8N5L3 O15023 Q86T69 Q5H9U2
Accessions EAW95850 EAW95851 Q7Z3T8 AB002303 BAA20764 AF434817 AAL30772 AK090896 AK127003 BAG54419 AL833087 CAD89968 AW952550 BC030808 AAH30808 BC032227 BX537424 CAD97666 BX649172 BX956000 CB854699 CR933621 CAI45932 DA216169 DB208042 DR005686 XM_005248632 XP_005248689 XM_005248634 XP_005248691 XM_011543752 XP_011542054 XM_011543753 XP_011542055 XM_011543754 XP_011542056 XM_011543755 XP_011542057 XM_011543756 XP_011542058 NM_001105251 NP_001098721 NM_001284236 NP_001271165 NM_001284237 NP_001271166 NM_014733 NP_055548
Function May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. {ECO:0000269|PubMed:11546807, ECO:0000269|PubMed:14613930}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11546807}. Early endosome membrane {ECO:0000269|PubMed:11546807}; Peripheral membrane protein {ECO:0000269|PubMed:11546807}. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
Tissue Specificity Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:11546807}.
Top Pathways TGF-beta signaling pathway, Endocytosis

ZFYVE16 CRISPR/Cas9 KO Plasmid (h) - sc-411338 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 HDR Plasmid (h) - sc-411338-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 Double Nickase Plasmid (h) - sc-411338-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 Double Nickase Plasmid (h2) - sc-411338-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 CRISPR Activation Plasmid (h) - sc-411338-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 CRISPR Activation Plasmid (h2) - sc-411338-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 Lentiviral Activation Particles (h) - sc-411338-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 Lentiviral Activation Particles (h2) - sc-411338-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZFYVE16 siRNA (h) - sc-91838 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZFYVE16 shRNA Plasmid (h) - sc-91838-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZFYVE16 shRNA (h) Lentiviral Particles - sc-91838-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU011731 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23203 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23203 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZFYVE16 siRNA (Human) - CRH6529 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFYVE16 RNAi - H00009765-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZFYVE16 - MBS829337 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFYVE16 (NM_014733.3) - SHH452456 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ZFYVE16(NM_014733.3) - SHL152300 from Creative biogene

Category siRNA
Species Reactivities Human

ZFYVE16 shRNA Plasmid (Human) - CHH6529 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFYVE16 miRNA 3'UTR clone - MiUTR1H-11443 from Creative biogene

Species Reactivities Human
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