ZFYVE16

Gene Symbol	ZFYVE16
Entrez Gene	9765
Alt Symbol	PPP1R69
Species	Human
Gene Type	protein-coding
Description	zinc finger, FYVE domain containing 16
Other Description	endosome-associated FYVE-domain protein|protein phosphatase 1, regulatory subunit 69|zinc finger FYVE domain-containing protein 16
Swissprots	Q8NEK3 Q7LAU7 Q7Z3T8 Q8N5L3 O15023 Q86T69 Q5H9U2
Accessions	EAW95850 EAW95851 Q7Z3T8 AB002303 BAA20764 AF434817 AAL30772 AK090896 AK127003 BAG54419 AL833087 CAD89968 AW952550 BC030808 AAH30808 BC032227 BX537424 CAD97666 BX649172 BX956000 CB854699 CR933621 CAI45932 DA216169 DB208042 DR005686 XM_005248632 XP_005248689 XM_005248634 XP_005248691 XM_011543752 XP_011542054 XM_011543753 XP_011542055 XM_011543754 XP_011542056 XM_011543755 XP_011542057 XM_011543756 XP_011542058 NM_001105251 NP_001098721 NM_001284236 NP_001271165 NM_001284237 NP_001271166 NM_014733 NP_055548
Function	May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. {ECO:0000269|PubMed:11546807, ECO:0000269|PubMed:14613930}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11546807}. Early endosome membrane {ECO:0000269|PubMed:11546807}; Peripheral membrane protein {ECO:0000269|PubMed:11546807}. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
Tissue Specificity	Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:11546807}.
Top Pathways	TGF-beta signaling pathway, Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ZFYVE16 protein (His-DHFR tag) - ab127797 from Abcam Category Protein Source E. coli Species Human

ZFYVE16 Antibody Blocking Peptide - LS-E7744 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ZFYVE16 Protein - H00009765-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ZFYVE16 Protein - H00009765-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ZFYVE16-Antibody-N-term-Blocking-Peptide - BP5120a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZFYVE16 - H00009765-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZFYVE16 - H00009765-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZFYVE16 - H00009765-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ZFYVE16 - H00009765-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ZFYVE16 fusion protein - Ag3811 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ZFYVE16, GST-tagged - ZFYVE16-3804H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Zinc finger FYVE domain-containing protein 16(ZFYVE16) ,partial - CSB-YP800100HU CSB-EP800100HU CSB-BP800100HU CSB-MP800100HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZFYVE16 Protein - abx163928 from Abbexa Category Protein Species Human

Zinc finger FYVE domain-containing protein 16(ZFYVE16) ,partial, Recombinant Protein - MBS1425760 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZFYVE16 Recombinant Protein Antigen - NBP1-81517PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFYVE16 Recombinant Protein Antigen - NBP1-81516PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFYVE16 Peptide, Human - M34GP17813H from Creative Peptides Category Peptide Source Synthetic. Species Human

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