Gene Symbol | PIGZ |
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Entrez Gene | 80235 |
Alt Symbol | GPI-MT-IV, PIG-Z, SMP3 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class Z |
Other Description | GPI mannosyltransferase 4|GPI mannosyltransferase IV|SMP3 mannosyltransferase|dol-P-Man dependent GPI mannosyltransferase|phosphatidylinositol glycan, class Z|phosphatidylinositol-glycan biosynthesis class Z protein |
Swissprots | Q86VD9 Q9H9G6 |
Accessions | EAW53618 Q86VD9 AK022830 BAB14263 AK296867 BAG59430 BC018804 BC044640 AAH44640 BG760692 BX493581 DA736224 XM_006713758 XP_006713821 XM_011513190 XP_011511492 XM_011513191 XP_011511493 XM_011513192 XP_011511494 NM_025163 NP_079439 |
Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues. {ECO:0000269|PubMed:15208306}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15208306}; Multi-pass membrane protein {ECO:0000269|PubMed:15208306}. |
Tissue Specificity | Widely expressed at low level, with highest level in brain and colon. {ECO:0000269|PubMed:15208306}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
Human PIGZ full length protein - ab164233 from Abcam
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PIGZ Antibody Blocking Peptide - LS-E15053 from LifeSpan Bioscience
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Recombinant Human PIGZ Protein - H00080235-P01 from Novus Biologicals
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PIGZ Blocking Peptide - 33R-9694 from Fitzgerald
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PIGZ - H00080235-P01-10 from Acris Antibodies
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PIGZ - H00080235-P01-25 from Acris Antibodies
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PIGZ fusion protein - ag10969 from Proteintech Group
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PIGZ fusion protein - Ag11259 from Proteintech Group
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Recombinant Human PIGZ, GST-tagged - PIGZ-1713H from Creative Biomart
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PIGZ Recombinant Protein Antigen - NBP2-32502PEP from Novus Biologicals
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PIGZ Protein - NBP2-32394PEP from Novus Biologicals
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PIGZ-Antibody-C-term-Blocking-peptide - BP5778b from Abgent, a WuXi AppTec company
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PIGZ Peptide, Human - M34GP11774H from Creative Peptides
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GPI mannosyltransferase 4 (smp3), Recombinant Protein - MBS7030176 from MyBioSource
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GPI mannosyltransferase 4 (smp3), Recombinant Protein - MBS7030177 from MyBioSource
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GPI mannosyltransferase 4 (SMP3), Recombinant Protein - MBS7030178 from MyBioSource
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GPI mannosyltransferase 4 (smp3), Recombinant Protein - MBS7030179 from MyBioSource
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GPI mannosyltransferase 4 (SMP3), Recombinant Protein - MBS7030180 from MyBioSource
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