Gene Symbol | PIGZ |
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Entrez Gene | 80235 |
Alt Symbol | GPI-MT-IV, PIG-Z, SMP3 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class Z |
Other Description | GPI mannosyltransferase 4|GPI mannosyltransferase IV|SMP3 mannosyltransferase|dol-P-Man dependent GPI mannosyltransferase|phosphatidylinositol glycan, class Z|phosphatidylinositol-glycan biosynthesis class Z protein |
Swissprots | Q86VD9 Q9H9G6 |
Accessions | EAW53618 Q86VD9 AK022830 BAB14263 AK296867 BAG59430 BC018804 BC044640 AAH44640 BG760692 BX493581 DA736224 XM_006713758 XP_006713821 XM_011513190 XP_011511492 XM_011513191 XP_011511493 XM_011513192 XP_011511494 NM_025163 NP_079439 |
Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues. {ECO:0000269|PubMed:15208306}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15208306}; Multi-pass membrane protein {ECO:0000269|PubMed:15208306}. |
Tissue Specificity | Widely expressed at low level, with highest level in brain and colon. {ECO:0000269|PubMed:15208306}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-Z (C-14) - sc-99592 from Santa Cruz Biotechnology
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PIG-Z (N-16) - sc-99594 from Santa Cruz Biotechnology
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Anti-PIGZ antibody - ab188512 from Abcam
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Anti-PIGZ Antibody (aa36-85) - LS-C110600 from LifeSpan Bioscience
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PIGZ Antibody - NBP2-32394 from Novus Biologicals
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PIGZ Antibody - NBP1-69251 from Novus Biologicals
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PIGZ Antibody - NBP2-32502 from Novus Biologicals
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Anti-PIGZ antibody produced in rabbit - SAB2101807 from Sigma-Aldrich
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Anti-PIGZ antibody produced in rabbit - HPA059920 from Sigma-Aldrich
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Anti-PIGZ antibody produced in rabbit - HPA058599 from Sigma-Aldrich
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PIGZ antibody - N-terminal region (ARP41020_P050) - ARP41020_P050 from Aviva Systems Biology
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PIGZ antibody - 70R-7100 from Fitzgerald
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PIGZ antibody - 70R-19287 from Fitzgerald
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PIGZ antibody - 17384-1-AP from Acris Antibodies
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PIGZ antibody - 17384-1-AP from Proteintech Group
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PIGZ Antibody - GWB-MN669C from Genway Biotech
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Anti-PIGZ monoclonal antibody - DCABH-201258 from Creative Diagnostics
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phosphatidylinositol glycan anchor biosynthesis, class Z , Polyclonal Antibody - MBS712809 from MyBioSource
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PIGZ antibody, N-term - GTX47247 from GeneTex
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PIGZ, Polyclonal Antibody - MBS5301849 from MyBioSource
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PIGZ, Polyclonal Antibody - MBS5301209 from MyBioSource
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PIGZ Antibody - SH-A14520 from Novatein Biosciences
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PIGZ antibody - TA343937 from Acris Antibodies
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PIGZ Antibody,Biotin conjugated - CSB-PA773038LD01HU from Cusabio
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PIGZ Antibody,FITC conjugated - CSB-PA773038LC01HU from Cusabio
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