TSHZ3

Gene Symbol TSHZ3
Entrez Gene 57616
Alt Symbol TSH3, ZNF537
Species Human
Gene Type protein-coding
Description teashirt zinc finger homeobox 3
Other Description teashirt 3|teashirt family zinc finger 3|teashirt homolog 3|zinc finger protein 537
Swissprots Q63HK5 Q9P254 Q9H0G6
Accessions Q63HK5 AB040907 BAA95998 AI015687 AK291466 BAF84155 AK293267 BAG56797 AL136805 CAB66739 AM393571 CAL38448 BC127095 AAI27096 BC127096 AAI27097 BX648745 CAH56184 CN256026 NM_020856 NP_065907
Function Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up- regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter. {ECO:0000269|PubMed:19343227}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:19343227}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with APBB1 in axonal growth cone (By similarity). Colocalizes with APBB1 in the nucleus. {ECO:0000250}.
Tissue Specificity Expressed in brain; strongly reduced in post- mortem elderly subjects with Alzheimer disease. {ECO:0000269|PubMed:18776146, ECO:0000269|PubMed:19343227}.

TSHZ3 (C-20) - sc-79168 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TSHZ3 (C-20): sc-79168. Western blot analysis of TSHZ3 expression in NIH/3T3 whole cell lysate.

TSHZ3 (N-16) - sc-79171 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TSHZ3 (N-16): sc-79171. Western blot analysis of TSHZ3 expression in A549 (A), C2C12 (B), HeLa (C), F9 (D) and NTERA-2 cl.D1 (E) whole cell lysates and mouse brain tissue extract (F).

TSHZ3 (K-22) - sc-134132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
TSHZ3 (K-22): sc-134132. Western blot analysis of TSHZ3 expression in A549 whole cell lysate.

Anti-ZNF537 antibody - ab28483 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ZNF537 antibody - N-terminal - ab176117 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of mouse brain tissue labeling ZNF537 with ab176117 at 2.5 μg/ml.

Anti-TSHZ3 Antibody (N-Terminus) IHC-plus™ - LS-B8806 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TSHZ3 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-TSHZ3 Antibody (aa466-515) - LS-C29876 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Lung Lysate

ZNF537 Antibody - NBP1-92629 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZNF537 Antibody [NBP1-92629] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.

ZNF537 Polyclonal Antibody - bs-8540R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TSHZ3 antibody produced in rabbit - HPA008834 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TSHZ3: <B>Cat. No. HPA008834</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human fallopian tube tissue showing nuclear positivity in glandular cells.

Anti-TSHZ3 antibody produced in rabbit - SAB3500761 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
<B>Immunoblotting</B><BR/>Anti-TSHZ3; <B>Cat. No. SAB3500761</B>; Western blot analysis of TSHZ3 in Mouse brain tissue lysate with TSHZ3 antibody at 1 μ/mL in (A) the absence and (B) the presence of blocking peptide.

Anti-ZNF537 antibody produced in rabbit - AV32963 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: fetal lung (<B>Cat. No. AV32963</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal lung

ZNF537 antibody - middle region (ARP32963_P050) - ARP32963_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TSHZ3 antibody - orb75765 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of mouse brain tissue lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide using TSHZ3 antibody

TSHZ3 antibody - orb1365 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

TSHZ3 Antibody - abx121232 from Abbexa

Host Rabbit
Clonality Polyclonal

TSHZ3 / ZNF537 antibody - 25018-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse brain tissue were subjected to SDS PAGE followed by western blot with 25018-1-AP( TSHZ3 Antibody) at dilution of 1:600

TSHZ3 / ZNF537 antibody - AP42160PU-N from Acris Antibodies

Prices $340.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Lung; WB Suggested Anti-ZNF537 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Lung; ZNF537 antibody - middle region (AP42160PU-N) in Human Lung cells using Western Blot

TSHZ3 / ZNF537 (N-term) antibody - AP55632PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of TSHZ3 in mouse brain tissue with TSHZ3 / ZNF537 antibody Cat.-No. AP55632PU-N at 2.5 µg/ml.

TSHZ3 / ZNF537 antibody - H00057616-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

TSHZ3 Antibody - 6759 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TSHZ3 in mouse brain tissue lysate with TSHZ3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

ZNF537 Antibody - 27-755 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Lung at 0.2-1 ug/ml.

TSHZ3 antibody - 25018-1-AP from Proteintech Group

Prices $279.00
Sizes con: 74 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse brain tissue were subjected to SDS PAGE followed by western blot with 25018-1-AP( TSHZ3 Antibody) at dilution of 1:600

TSHZ3 Antibody - 25459 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of TSHZ3 in mouse brain tissue lysate with TSHZ3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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