TSHZ3

Gene Symbol TSHZ3
Entrez Gene 57616
Alt Symbol TSH3, ZNF537
Species Human
Gene Type protein-coding
Description teashirt zinc finger homeobox 3
Other Description teashirt 3|teashirt family zinc finger 3|teashirt homolog 3|zinc finger protein 537
Swissprots Q63HK5 Q9P254 Q9H0G6
Accessions Q63HK5 AB040907 BAA95998 AI015687 AK291466 BAF84155 AK293267 BAG56797 AL136805 CAB66739 AM393571 CAL38448 BC127095 AAI27096 BC127096 AAI27097 BX648745 CAH56184 CN256026 NM_020856 NP_065907
Function Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up- regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter. {ECO:0000269|PubMed:19343227}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:19343227}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with APBB1 in axonal growth cone (By similarity). Colocalizes with APBB1 in the nucleus. {ECO:0000250}.
Tissue Specificity Expressed in brain; strongly reduced in post- mortem elderly subjects with Alzheimer disease. {ECO:0000269|PubMed:18776146, ECO:0000269|PubMed:19343227}.

TSHZ3 CRISPR/Cas9 KO Plasmid (h) - sc-410072 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 HDR Plasmid (h) - sc-410072-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 Double Nickase Plasmid (h) - sc-410072-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 Double Nickase Plasmid (h2) - sc-410072-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 CRISPR Activation Plasmid (h) - sc-410072-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 CRISPR Activation Plasmid (h2) - sc-410072-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 Lentiviral Activation Particles (h) - sc-410072-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 Lentiviral Activation Particles (h2) - sc-410072-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TSHZ3 siRNA (h) - sc-76764 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TSHZ3 shRNA Plasmid (h) - sc-76764-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TSHZ3 shRNA (h) Lentiviral Particles - sc-76764-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF537 RNAi - H00057616-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU118891 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22092 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22092 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12706 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12706

TSHZ3 siRNA (Human) - CRJ1584 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TSHZ3 - MBS8200314 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TSHZ3 (NM_020856.2) - SHH436128 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TSHZ3(NM_020856.2) - SHL099246 from Creative biogene

Category siRNA
Species Reactivities Human

Human TSHZ3 siRNA - orb272085 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TSHZ3 shRNA Plasmid (Human) - CHJ1584 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TSHZ3 miRNA 3'UTR clone - MiUTR1H-10811 from Creative biogene

Species Reactivities Human
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