Gene Symbol | TRIAP1 |
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Entrez Gene | 51499 |
Alt Symbol | HSPC132, MDM35, P53CSV, WF-1 |
Species | Human |
Gene Type | protein-coding |
Description | TP53 regulated inhibitor of apoptosis 1 |
Other Description | TP53-regulated inhibitor of apoptosis 1|mitochondrial distribution and morphology 35 homolog|p53-inducible cell-survival factor|protein 15E1.1 |
Swissprots | Q5RKS5 Q6LCA7 O43715 B2R4Z7 |
Accessions | EAW98192 O43715 AF161481 AAF29096 AK312006 BAG34944 BC002638 AAH02638 BC055313 AAH55313 CB141335 DQ893091 ABM84017 DQ896363 ABM87362 U75688 AAR00584 NM_016399 NP_057483 |
Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. {ECO:0000269|PubMed:15735003, ECO:0000269|PubMed:23931759}. |
Subcellular Location | Cytoplasm, perinuclear region. Mitochondrion. Mitochondrion intermembrane space. |
p53CSV (C-17) - sc-139544 from Santa Cruz Biotechnology
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p53CSV (E-14) - sc-139542 from Santa Cruz Biotechnology
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p53CSV (G-18) - sc-139543 from Santa Cruz Biotechnology
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Anti-TRIAP1 Antibody - LS-C346398 from LifeSpan Bioscience
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HSPC132 Antibody - NBP2-30707 from Novus Biologicals
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Anti-TRIAP1 antibody produced in rabbit - HPA053640 from Sigma-Aldrich
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TRIAP1 Polyclonal Antibody - A7313 from ABclonal
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TRIAP1 Antibody - abx005520 from Abbexa
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TRIAP1 antibody - 15351-1-AP from Acris Antibodies
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Anti-TRIAP1, Polyclonal Antibody - 25-A7313 from ARP American Research Products
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Anti-TRIAP1 antibody - STJ29452 from St John's Laboratory Ltd
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TRIAP1 antibody - 15351-1-AP from Proteintech Group
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TRIAP1 , Polyclonal Antibody - MBS9127759 from MyBioSource
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TRIAP1 - A7313 from NeoScientific
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Anti-TRIAP1 polyclonal antibody - CABT-BL059 from Creative Diagnostics
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TRIAP1 Antibody - CSB-PA024443ESR2HU from Cusabio
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TRIAP1 Antibody - CSB-PA024443ESR1HU from Cusabio
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TRIAP1 polyclonal antibody - BS70786 from Bioworld Technology
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TRIAP1 Polyclonal Antibody - EAP3522 from Elabscience
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anti-TRIAP1 antibody - A008964 from Biobool
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TRIAP1 Polyclonal Antibody - A7313 from ARP American Research Products
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Anti-TRIAP1 Antibody IHC-plus⢠- LS-B14596 from LifeSpan Bioscience
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Anti-TRIAP1 Antibody - LS-C661242 from LifeSpan Bioscience
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TRIAP1, Polyclonal Antibody - MBS7045385 from MyBioSource
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TRIAP1, Polyclonal Antibody - MBS2540980 from MyBioSource
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