Gene Symbol | TRIAP1 |
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Entrez Gene | 51499 |
Alt Symbol | HSPC132, MDM35, P53CSV, WF-1 |
Species | Human |
Gene Type | protein-coding |
Description | TP53 regulated inhibitor of apoptosis 1 |
Other Description | TP53-regulated inhibitor of apoptosis 1|mitochondrial distribution and morphology 35 homolog|p53-inducible cell-survival factor|protein 15E1.1 |
Swissprots | Q5RKS5 Q6LCA7 O43715 B2R4Z7 |
Accessions | EAW98192 O43715 AF161481 AAF29096 AK312006 BAG34944 BC002638 AAH02638 BC055313 AAH55313 CB141335 DQ893091 ABM84017 DQ896363 ABM87362 U75688 AAR00584 NM_016399 NP_057483 |
Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis. {ECO:0000269|PubMed:15735003, ECO:0000269|PubMed:23931759}. |
Subcellular Location | Cytoplasm, perinuclear region. Mitochondrion. Mitochondrion intermembrane space. |
Human TRIAP1 full length protein - ab176057 from Abcam
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TRIAP1 Protein - GTX110986-pro from GeneTex
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TRIAP1 protein (His tag) - 80R-3564 from Fitzgerald
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TRIAP1 (1-76, His-tag) - AR51251PU-N from Acris Antibodies
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TRIAP1 (1-76, His-tag) - AR51251PU-S from Acris Antibodies
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TRIAP1, 1-76aa, Human, His tag, E.coli - 01-P2431 from ARP American Research Products
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TRIAP1 fusion protein - Ag7597 from Proteintech Group
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TRIAP1 fusion protein - Ag7630 from Proteintech Group
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Recombinant human TRIAP1, His-tagged - TRIAP1-2431H from Creative Biomart
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Recombinant Human TRIAP1, GST-tagged - TRIAP1-3403H from Creative Biomart
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Recombinant Human TP53-regulated inhibitor of apoptosis 1(TRIAP1) - CSB-YP024443HU CSB-EP024443HU CSB-BP024443HU CSB-MP024443HU from Cusabio
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TRIAP1, 1-76aa, Human, His tag, E.coli - ATGP2431 from ATGen
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TP53 Regulated Inhibitor Of Apoptosis 1 Protein (Recombinant) - abx261206 from Abbexa
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TRIAP1 - TP301032 from Acris Antibodies
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Human TRIAP1 protein - orb260148 from Biorbyt
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HSPC132 Recombinant Protein Antigen - NBP2-30707PEP from Novus Biologicals
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TRIAP1 Peptide, Human - M34GP16559H from Creative Peptides
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TRIAP1 - PAT-82430-1 from Nordic BioSite
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TRIAP1 - PAT-82430-2 from Nordic BioSite
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Human TRIAP1 protein - orb54456 from Biorbyt
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TP53 Regulated Inhibitor Of Apoptosis 1, Human Recombinant - 228-21879-1 from RayBiotech
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TRIAP1 Recombinant Protein (Human) (OPCA04943) - OPCA04943 from Aviva Systems Biology
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Recombinant Human TP53-regulated inhibitor of apoptosis 1 (TRIAP1) - RPC22173 from Biomatik
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